Results 151 to 160 of about 1,615,733 (299)

Covariate-adjusted SMI by the UA quartiles (mean ± SEM, n = 3079).

open access: yes, 2016
Covariate-adjusted SMI by the UA quartiles (mean ± SEM, n = 3079).
Yu-ming Chen (330176)   +5 more
core   +1 more source

Biochemically Constrained Multi‐Omics Integration Reveals Protein–Metabolite Dependencies Across Diseases

open access: yesAdvanced Science, EarlyView.
ProMetNet introduces a biologically constrained deep learning framework for proteo‐metabolomic integration by embedding Reactome‐derived pathway topology into neural networks. It captures non‐linear molecular dependencies and pathway‐level metabolic reorganization, enabling interpretable discrimination.
Minghui Zhao   +6 more
wiley   +1 more source

How Balanced Should Causal Covariates Be?

open access: yes
Covariate balancing is a popular technique for controlling confounding in observational studies. It finds weights for the treatment group which are close to uniform, but make the group's covariate means (approximately) equal to those of the entire sample.
Kaul, Shiva, Kim, Min-Gyu
openaire   +2 more sources

Covariate-Adjusted Mean Number of Physician Visits at Each Follow-Up Period for Appraisal Groups.

open access: yes, 2016
Covariate-Adjusted Mean Number of Physician Visits at Each Follow-Up Period for Appraisal Groups.
Reinhard Pekrun (282996)   +5 more
core   +1 more source

NICE: A Two‐Step Non‐Invasive Framework for Embryo cfDNA Read Enrichment and Quality Assessment

open access: yesAdvanced Science, EarlyView.
The non‐invasive NICE framework, built on an ensemble stacking machine learning model, prioritizes embryos by analyzing cell‐free DNA from spent culture medium. By integrating multimodal signals, including genomic and epigenetic profiles, this automated approach standardizes morphological assessment without human bias, paving the way for more precise ...
Xueya Zhou   +6 more
wiley   +1 more source

Tau Aggregate Imaging and Transcriptomics of Alzheimer's Disease Brain at Different Stages of Disease

open access: yesAdvanced Science, EarlyView.
The protein aggregates and gene expression in the middle temporal gyrus (MTG) and somatosensory cortex (SOM) of the postmortem brains of 13 Alzheimer's disease patients were studied in detail, revealing that small hyperphosphorylated tau aggregates increase with Braak stage driven by microglial inflammation.
Elizabeth A. English   +9 more
wiley   +1 more source

Estimating the causal effects of exposure mixtures: a generalized propensity score method

open access: yesBMC Medical Research Methodology
Background In environmental epidemiology and many other fields, estimating the causal effects of multiple concurrent exposures holds great promise for driving public health interventions and policy changes. Given the predominant reliance on observational
Qian Gao   +7 more
doaj   +1 more source

Sample Size for Confidence Interval of Covariate-Adjusted Mean Difference

open access: yes, 2010
This article provides a way to determine adequate sample size for the confidence interval of covariate-adjusted mean difference in randomized experiments.
Xiaofeng Steven Liu
core   +1 more source

14‐3‐3γ Protects Against Postoperative Cognitive Dysfunction by Regulating Tau Thr205 Phosphorylation and Synaptic Integrity

open access: yesAdvanced Science, EarlyView.
Integrative multi‐cohort analyses identify 14‐3‐3γ as a biomarker and regulator of cognitive vulnerability. Experimental studies show that 14‐3‐3γ loss is associated with Tau Thr205 phosphorylation, synaptic dysfunction, and cognitive impairment, while genetic overexpression or pharmacological stabilization of 14‐3‐3γ confers protective effects in ...
Shouqiang Zhu   +5 more
wiley   +1 more source

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