Results 41 to 50 of about 1,894 (264)
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Jesus and the Jewish covenants
Jesus established a New Covenant which we commemorate regularly at the Holy Communion. This New Covenant can only be fully appreciated in the context of the Old Testament (OT).
Volker Kessler
doaj +1 more source
Covenant design in financial contracts: a case study of the private equity acquisition of HCA
A buyout deal involves several parties, including private equity firms, the target company, and lending banks. All these parties are legally connected by contractual arrangements, and covenants among all interest parties are important.
Tzu-Wen Wei +3 more
doaj +1 more source
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso +5 more
wiley +1 more source
Financial Intermediation and Fixed Capital Formation in Zimbabwe
Business sustainability is heavily constrained by the shortage of affordable finance of adequate duration and quality. This affects producers and traders' capacity to reorganize their production and exchange systems to attain dynamic competitiveness ...
Upenyu Sakarombe, Lloyd Badze
doaj +1 more source
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source
Tradition, heritage, memory, historical consciousness, identity are categories of memory studies, interest in which is constantly growing today. In this article the author attempts to examine the ancient «covenants of the fathers» described by Aristotle ...
Марія Загурська
doaj +1 more source
Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
Small RNA pathways in mammalian oocytes
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley +1 more source
This article examines the roles that religious pluralism and civic rights played in Prophet Muhammad’s vision of a “Muslim nation”. I demonstrate how Muhammad desired a pluralistic society in which citizenship and equal rights were granted to all people ...
Craig Considine
doaj +1 more source

