Results 221 to 230 of about 589,878 (312)

Human Brain Vasculature‐on‐a‐Chip Model Constructed With Microvessels Isolated From Cryopreserved Postmortem Human Brain Tissue

Advanced Healthcare Materials, EarlyView.
This manuscript describes the cultivation of viable microvessels from cryopreserved human brain tissue. When embedded in hydrogels and cultured in microfluidic devices, these microvessels exhibit complex architectures reminiscent of arterioles and capillaries, can be perfused, and display intact barrier function. Collectively, these results demonstrate
Brian J. O'Grady, A. Scott McCall, Samuel Cullison, Daniel Chavarria, Matthew S. Schrag, Ethan S. Lippmann   +5 more
wiley   +1 more source

Interrow cover crops in a semi-arid vineyard increase plant beneficial functional potential of the soil microbiome, both in vine rows and interrows, a benefit that increases with cover crop duration. [PDF]

Environ Microbiome
Rocha FI, Rodriguez-Ramos JC, Fernando M, Hale L.   +3 more
europepmc   +1 more source

Dual‐Peptide Nanoplatform: Mesoporous Silica Nanoparticles Functionalized With a Cell‐Penetrating Peptide and Loaded With Rationally Designed Antimicrobial Peptides for Tuberculosis Therapy

Advanced Healthcare Materials, EarlyView.
Machine learning–guided engineering of a plectasin‐derived peptide yields DC05, a potent antimycobacterial candidate. Encapsulation into tuftsin‐functionalized mesoporous silica nanoparticles enhances intracellular delivery, stability, and activity against Mycobacterium tuberculosis while maintaining low cytotoxicity and minimal hemolysis. The combined
Christian S. Carnero Canales, Cesar Augusto Roque‐Borda, Ana Carolina Cerqueira Negri, Oswaldo Ramirez Delgado, Letícia Oliveira Catarin Nunes, Flávia Aparecida Resende, Hernane Barud, Norival Alves Santos‐Filho, Saulo Santesso Garrido, Karen Cristina Oliveira, Alexandra Ivo de Medeiros, Rafael Miguel Sábio, Fernando Rogério Pavan   +12 more
wiley   +1 more source

Winter cover crop suppression methods influence on sunflower growth and rhizosphere communities. [PDF]

Front Microbiol
Morales ME, Allegrini M, Basualdo J, Iocoli GA, Villamil MB, Zabaloy MC.   +5 more
europepmc   +1 more source

Paracrine Factor Local Gradient‐Generating System for Engineering Perfusable Vascularized Hepatocyte Tissues with Perfusion‐Induced Proliferation

Advanced Healthcare Materials, EarlyView.
A paracrine factor local gradient (PFLG)‐generating system enables microvessel penetration across 3D hepatocyte tissues. The resulting vascularized constructs recapitulate hepatic sinusoidal hepatocyte—endothelial contact architecture and enhance hepatic functions in vitro.
Yen‐Hsiang Huang, Tadahiro Yamashita, Ryo Sudo   +2 more
wiley   +1 more source

U.S. cereal rye winter cover crop growth database. [PDF]

Sci Data
Huddell AM, Thapa R, Marcillo GS, Abendroth LJ, Ackroyd VJ, Armstrong SD, Asmita G, Bagavathiannan MV, Balkcom KS, Basche A, Beam S, Bradley K, Canisares LP, Darby H, Davis AS, Devkota P, Dick WA, Evans JA, Everman WJ, de Almeida TF, Flessner ML, Fultz LM, Gailans S, Hashemi M, Haymaker J, Helmers MJ, Jordan N, Kaspar TC, Ketterings QM, Kladivko E, Kravchenko A, Law EP, Lazaro L, Leon RG, Liebert J, Lindquist J, Loria K, McVane JM, Miller JO, Mulvaney MJ, Nkongolo NV, Norsworthy JK, Parajuli B, Pelzer C, Peterson C, Poffenbarger H, Poudel P, Reiter MS, Ruark M, Ryan MR, Samuelson S, Sawyer JE, Seehaver S, Shergill LS, Upadhyaya YR, VanGessel M, Waggoner AL, Wallace JM, Wells S, White C, Wolters B, Woodley A, Ye R, Youngerman E, Needelman BA, Mirsky SB.   +65 more
europepmc   +1 more source

Skin‐Interfaced Therapeutic Patches for Wound Fluid Management and Transdermal Drug Delivery

Advanced Healthcare Materials, EarlyView.
This study presents an integrated skin‐interfaced device combining microfluidics, hydrogel film technology, flexible electronics, and iontophoresis‐based transdermal delivery of PDRN to enhance wound healing. The device effectively manages wound fluid, maintains optimal moisture, and non‐invasively delivers therapeutic drugs.
Dongjun Han, Donghyun Kim, Haram Lee, Dong‐Wook Park, Sung Soo Kwak, Joohee Kim   +5 more
wiley   +1 more source

Cover crop systems impact on biomass production, carbon-to-nitrogen ratio, forage quality, and soil health in a semi-arid environment. [PDF]

Heliyon
Opoku A, Ogunleye AM, Solomon JKQ, Payne WA.   +3 more
europepmc   +1 more source

siRNA Delivery via Cross‐Linked Gelatin Microparticles Enables Targeted Modulation of Osteogenic‐Vascular Cross‐Talk: An Advanced Human 3D in Vitro Test System for Therapeutic siRNA

Advanced Healthcare Materials, EarlyView.
Osteogenic‐angiogenic cross‐talk is a vital prerequisite for vascularized bone regeneration. In this study, we investigated the effects of siRNA‐mediated silencing of two inhibitory proteins, Chordin and WWP‐1, via CaP‐NP‐loaded gelatin microparticles in osteogenically differentiated microtissues.
Franziska Mitrach, Jonas Kubat, Stefan Simm, Alexandra H. Springwald, Burak Demir, Anton Liebezeit, Michael C. Hacker, Michaela Schulz‐Siegmund   +7 more
wiley   +1 more source

Pearl Millet Cover Crop Extract Inhibits the Development of the Weed Ipomoea grandifolia by Inducing Oxidative Stress in Primary Roots and Affecting Photosynthesis Efficiency. [PDF]

Plants (Basel)
Mantovanelli GC, Silva AA, Ricardo LL, Kagami FL, de Almeida JD, Barbosa MC, Mito MS, Contesoto IC, da Costa Menezes PVM, Stulp GF, Moreno BP, Pereira Valeze FA, de Oliveira Junior RS, Baldoqui DC, Ishii Iwamoto EL.   +14 more
europepmc   +1 more source