Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
Towards sustainable maize production in the U.S. upper Midwest with interseeded cover crops.
The incorporation of cover crops into the maize (Zea mays L.)-soybean [Glycine max (L.) Merr.] rotation in the U.S. upper Midwest may improve sustainability.
Hannah L Rusch +5 more
doaj +1 more source
Protocol for quantifying miRNA trafficking across the endosomal membrane
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh +2 more
wiley +1 more source
Wpływ roślin ochronnych na plon masy nadziemnej wsiewek międzyplonowych
The aim of the present research was to compare the influence of four cover crops plants and six undersown crop cultivars cultivated on light soil in the Lublin region.
Robert Kuraszkiewicz, Edward Pałys
doaj
Detection and Mapping of Cover Crops Using Sentinel-1 SAR Remote Sensing Data
Cover crops are intermediary crops planted in between two main cash crops. They play a role in limiting nitrate leaching into groundwater. Currently, there is no database pertaining to cover crops despite their importance. The development period of cover
Sami Najem +4 more
doaj +1 more source
GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta +7 more
wiley +1 more source
Wpływ wsiewek międzyplonowych na zachwaszczenie łanu roślin ochronnych na glebie lekkiej
The field research was carried out in the years 19931996 at the Agricultural Experimental Station of Bezek belonging to the Agricultural University of Lublin. The experiment was localized on good rye complex.
Robert Kuraszkiewicz, Edward Pałys
doaj
RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu +21 more
wiley +1 more source
Cover Crops and Nitrogen Fertilization in Maize on the Productive Performance of Crop [PDF]
The use of conservation practices for sustainable agriculture production has grown in the last decades, mainly due to the no-tillage and the cover crops.
Rafael Ribeiro Guelere +6 more
doaj +1 more source

