Results 41 to 50 of about 1,621,757 (315)
Background: Since its inception in 1974, the Essential Programme on Immunization (EPI) has achieved remarkable success, averting the deaths of an estimated 154 million children worldwide through routine childhood vaccination. However, more recent decades
Stefano Di Bella +3 more
core +2 more sources
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Материалы по археологии и истории античного и средневекового Крыма, 2019 The source, revealing manifestation of peasants’ mentality, is published and analyzed in the article by the example of the cave functioning near the village of Malaya Znamenka of Kamenskaya volost in Melitopol parish of Taurida Governorate.
V.V. Stepkin
doaj +1 more source
BMJ Open, 2020 Objective This study explored the illness experiences and healthcare-seeking behaviour of a cross-section of street dwellers of Dhaka City for designing a customised intervention.Design A qualitative exploratory study of a sample of street dwellers of ...
Nahitun Naher +5 more
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
CoRRWe introduce and study coverage games - a novel framework for multi-agent planning in settings in which a system operates several agents but does not have full control on them, or interacts with an environment that consists of several agents. The game is played between a coverer, who has a set of objectives, and a disruptor.
Kupferman, Orna, Shenwald, Noam
openaire +3 more sources
Recognizing Coverage Functions [PDF]
SIAM Journal on Discrete Mathematics, 2015 Summary: A coverage function \(f\) over a ground set \([m]\) is associated with a universe \(U\) of weighted elements and \(m\) sets \(A_1,\dots,A_m \subseteq U\), and for any \(T\subseteq [m]\), \(f(T)\) is defined as the total weight of the elements in the union \(\bigcup_{j\in T} A_j\).
Deeparnab Chakrabarty, Zhiyi Huang 0002
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Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Vaccine: XBackground: COVID-19 vaccine rollout has prioritized high risk populations, including children with chronic health conditions (CHC), who are at greater risk of severe illness and hospitalization if infected.
Arlanna Pugh +3 more
doaj +1 more source