Results 71 to 80 of about 862,801 (304)

Integrative miRNOMe profiling reveals the miR‐195‐5p–CHEK1 axis and its impact on luminal breast cancer outcomes

open access: yesMolecular Oncology, EarlyView.
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková   +14 more
wiley   +1 more source

Performance of NOMA-Based mmWave D2D Networks Under Practical System Conditions

open access: yesIEEE Access, 2021
This work elaborates the analysis on ergodic capacity, coverage probability, and average throughput for multi-user non-orthogonal multiple access (NOMA) based device-to-device communication networks, which operate in the millimeter-wave spectrum range ...
Leila Tlebaldiyeva   +3 more
doaj   +1 more source

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

open access: yesMolecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi   +12 more
wiley   +1 more source

Decrypting cancer's spatial code: from single cells to tissue niches

open access: yesMolecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik   +4 more
wiley   +1 more source

Optimal Mode Selection With Uplink Data Rate Maximization for D2D-Aided Underlaying Cellular Networks

open access: yesIEEE Access, 2016
The device-to-device (D2D) communication has been regarded as an effective technique for complementing and enhancing the conventional cellular systems owing to its capability of substantially improving both the spectral and power efficiencies of wireless
Jian Sun   +6 more
doaj   +1 more source

Neural network probability estimation for broad coverage parsing [PDF]

open access: yesProceedings of the tenth conference on European chapter of the Association for Computational Linguistics - EACL '03, 2003
We present a neural-network-based statistical parser, trained and tested on the Penn Treebank. The neural network is used to estimate the parameters of a generative model of left-corner parsing, and these parameters are used to search for the most probable parse.
openaire   +3 more sources

Finite random coverings of one-complexes and the Euler characteristic

open access: yes, 2014
This article presents an algebraic topology perspective on the problem of finding a complete coverage probability of a one dimensional domain $X$ by a random covering, and develops techniques applicable to the problem beyond the one dimensional case.
Komendarczyk, Rafal, Pullen, Jeffrey
core   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

A Penalized Likelihood Approach to Parameter Estimation with Integral Reliability Constraints

open access: yesEntropy, 2015
Stress-strength reliability problems arise frequently in applied statistics and related fields. Often they involve two independent and possibly small samples of measurements on strength and breakdown pressures (stress).
Barry Smith   +3 more
doaj   +1 more source

Explicit nonparametric confidence intervals for the variance with guaranteed coverage [PDF]

open access: yes, 2001
In this paper, we provide a method for constructing confidence intervals for the variance that exhibit guaranteed coverage probability for any sample size, uniformly over a wide class of probability distributions.
Romano, Joseph P., Wolf, Michael
core   +1 more source

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