The IFNγ‐CIITA‐MHC II axis modulates melanoma cell susceptibility to NK‐cell‐mediated cytotoxicity
Natural killer (NK) cells play a central role in anti‐melanoma immunity. However, melanoma cells adapt during co‐culture by upregulating CIITA and MHC II in response to interferon gamma (IFNγ), thereby evading NK‐cell lysis. Blocking IFNγ signaling or treatment with dimethyl fumarate/simvastatin counteracts this immune escape and maintains NK‐cell ...
Lena C. M. Krause +6 more
wiley +1 more source
Indoor Wi-Fi coverage measurement without spatial coordinates
In R16, 3GPP proposed that user devices could utilize the 4G/5G cellular networks to report the received signal strength indicator (RSSI) of Wi-Fi signal based on the existing minimization of drive test (MDT) technology, making it possible to measure the
XIE Zefeng +5 more
doaj +2 more sources
Deployment Strategies of Multiple Aerial BSs for User Coverage and Power Efficiency Maximization [PDF]
Unmanned aerial vehicle (UAV) based aerial base stations (BSs) can provide rapid communication services to ground users and are thus promising for future communication systems. In this paper, we consider a scenario where no functional terrestrial BSs are
Masouros, Christos, Sun, Jingcong
core +1 more source
Coverage and Rate Analysis for Unmanned Aerial Vehicle Base Stations with LoS/NLoS Propagation
The use of unmanned aerial vehicle base stations (UAV-BSs) as airborne base stations has recently gained great attention. In this paper, we model a network of UAV-BSs as a Poisson point process (PPP) operating at a certain altitude above the ground users.
Alzenad, Mohamed, Yanikomeroglu, Halim
core +1 more source
Diffusion‐based size determination of solute particles: a method adapted for postsynaptic proteins
We present a diffusion‐based approach for measuring the size of macromolecules and their complexes, and demonstrate its use on postsynaptic proteins. The method requires fluorescein‐labelled protein samples, a microfluidic device that maintains laminar flow for said samples, a microscope recording the emitted fluorescent signals, and an analytic ...
András László Szabó +7 more
wiley +1 more source
Interplay between RNA‐protein interactions and RNA structures in gene regulation
Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko +2 more
wiley +1 more source
The family of Clayton copulas is one of the most widely used Archimedean copulas for dependency measurement. A major drawback of this copula is that when it accounts for negative dependence, the copula is nonstrict and its support is dependent on the ...
Cooray Kahadawala
doaj +1 more source
Performance Analysis for User-Centric Dense Networks With mmWave
This paper focuses on the coverage probability and ergodic capacity for millimeter wave (mmWave) user-centric dense networks, where multiple access points (APs) consist of a virtual cell for each user equipment and transmit data with mmWave antennas ...
Jianfeng Shi +3 more
doaj +1 more source
The Improved Value-at-Risk for Heteroscedastic Processes and Their Coverage Probability [PDF]
A risk measure commonly used in financial risk management, namely, Value-at-Risk (VaR), is studied. In particular, we find a VaR forecast for heteroscedastic processes such that its (conditional) coverage probability is close to the nominal. To do so, we pay attention to the effect of estimator variability such as asymptotic bias and mean square error.
openaire +3 more sources
NOTCH2NLC Repeat Expansions in Parkinsonian Disorders: Clinical and Neuroimaging Characteristics
ABSTRACT Objective Neuronal intranuclear inclusion disease (NIID) is a neurodegenerative disorder caused by NOTCH2NLC GGC repeat expansions, with heterogeneous clinical manifestations, including parkinsonism. Recent studies have identified NOTCH2NLC repeat expansions in patients with Parkinson's disease (PD) and atypical parkinsonism (aPM), suggesting ...
Han‐Lin Chiang +7 more
wiley +1 more source

