Results 91 to 100 of about 236,678 (289)

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Applications of δ-Open Sets via Separation Axioms, Covering Properties, and Rough Set Models

Journal of Mathematics
In this article, we make use of δ-open sets to establish some topological concepts related to separation axioms and covering properties and to propose novel topological rough set models.
Tareq M. Al-Shami, Muneerah Al Nuwairan
doaj   +1 more source

EFFICIENT STORAGE AND COMPRESSION OF COVERING ARRAYS USING ADVANCED ENCODING TECHNIQUES

Journal of Engineering Science (Chişinău)
This paper introduced a novel storage format for covering arrays, designed to optimize file size through efficient compression techniques. The proposed format employed Asymmetric Numeral System (ANS) encoding for array data, as well as Run ...
CERVAC, Petru, SUDACEVSCHI, Viorica
doaj   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Macroscopic Mechanical Properties and Microstructure Characteristics of Solid Waste Base Capillary Retarded Field Covering Material

Buildings
In the practical operation of traditional landfills, compaction clay often experiences cracking, while the HDPE geomembrane may tear and bulge, resulting in a compromised performance of the landfill covering system.
Yifan He, Haijun Lu, Jirong Lan, Jiayu Ma, Mengyi Liu, Yiqie Dong   +5 more
doaj   +1 more source

Characterization of the coatings covering esthetic orthodontic archwires and their influence on the bending and frictional properties [PDF]

, 2016
Takeshi Muguruma, Masahiro Iijima, Toshihiro Yuasa, Kyotaro Kawaguchi, Itaru Mizoguchi   +4 more
openalex   +1 more source

Exploring Properties and Isomorphisms of Automorphism Groups in Regular Covering Spaces

, 2023
Kumari Sreeja S Nair
openalex   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source