Results 91 to 100 of about 1,281,596 (279)

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

An asymptotic dimension for metric spaces, and the 0-th Novikov-Shubin invariant

open access: yes, 2001
A nonnegative number d_infinity, called asymptotic dimension, is associated with any metric space. Such number detects the asymptotic properties of the space (being zero on bounded metric spaces), fulfills the properties of a dimension, and is invariant ...
Guido, Daniele, Isola, Tommaso
core  

ADDITIVE COVERS AND THE CANONICAL BASE PROPERTY

open access: yesThe Journal of Symbolic Logic, 2022
AbstractWe give a new approach to the failure of the Canonical Base Property (CBP) in the so far only known counterexample, produced by Hrushovski, Palacín and Pillay. For this purpose, we will give an alternative presentation of the counterexample as an additive cover of an algebraically closed field.
openaire   +3 more sources

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

On ideal sequence covering maps

open access: yesApplied General Topology, 2019
In this paper we introduce the concept of ideal sequence covering map which is a generalization of sequence covering map, and investigate some of its properties.
Sudip Kumar Pal   +2 more
doaj   +1 more source

Monotone covering properties and properties they imply

open access: yesTopology and its Applications, 2016
From the abstract: We study properties of spaces that were proven in an earlier paper of \textit{T. Chase} and \textit{G. Gruenhage} [Topology Appl. 160, No. 1, 45--49 (2013; Zbl 1264.54039)] to follow from monotonic metacompactness. We show that all of the results of that earlier paper that follow from the monotonic covering property follow just from ...
Chase, Timothy, Gruenhage, Gary
openaire   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Negative (and positive) circles in signed graphs: A problem collection

open access: yesAKCE International Journal of Graphs and Combinatorics, 2018
A signed graph is a graph whose edges are labeled positive or negative. The sign of a circle (cycle, circuit) is the product of the signs of its edges. Most of the essential properties of a signed graph depend on the signs of its circles. Here I describe
Thomas Zaslavsky
doaj   +1 more source

A very general covering property

open access: yes, 2011
v.2 largely expanded and improved; v.3: just pointed out that the definitions of Menger and Rothberger are nonstandard in the published journal ...
openaire   +4 more sources

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

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