Results 91 to 100 of about 274,570 (306)

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Seeding Performances of No-Till Seeders Equipped with Different Furrow Openers, Covering Components and Forward Speeds for Winter Wheat

open access: yesJournal of Agricultural Sciences, 2012
In the no-till method, seeds are placed in rows opened by furrow openers that can work under stubble field conditions, and are covered with soil and plant residue using covering components.
Ahmet Çelik, Sefa Altıkat
doaj   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Otimização de escala de trabalho para condutores de trem: sequenciamento de tarefas e alocação baseada em preferencia declarada [PDF]

open access: yes, 1997
Tese (Doutorado) - Universidade Federal de Santa Catarina, Centro TecnologicoEste trabalho tem como objetivo apresentar uma sistemática para o planejamento mensal de escalas de trabalho para condutores de trem, buscando uma distribuição mais equitativa ...
Constantino, Ademir Aparecido
core  

Semi-Hurewicz-Type properties in ditopological texture spaces

open access: yesOpen Mathematics, 2018
In this paper we will define and discuss semi-Hurewicz type covering properties in ditopological texture spaces. We consider the behaviour of semi-Hurewicz and co-semi-Hurewicz selection properties under direlation and difunction between ditopological ...
Ullah Hafiz, Khan Moiz ud Din
doaj   +1 more source

D-spaces and covering properties

open access: yesTopology and its Applications, 2005
A neighbourhood assignment on a topological space is a mapping \(\phi\) of \(X\) into the topology \(\tau\) of \(X\) such that \(x\in \phi(x)\) for each \(x \in X\). A space \(X\) is a D-space if, for every neighbourhood assignment \(\phi\) on \(X\), there exists a locally finite (in \(X\)) subset \(A\) of \(X\) such that the family \(\phi(A)\) covers \
openaire   +2 more sources

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Covering Properties and Cohen Forcing

open access: yes, 2007
We will show that adding Cohen reals preserves the covering property that every open cover has a σ-P Q refinement and deduce that adding Cohen reals preserves covering properties such as paracompactness, subparacompactness and ...
Iwasa, Akira
core  

Monotone covering properties and properties they imply

open access: yesTopology and its Applications, 2016
From the abstract: We study properties of spaces that were proven in an earlier paper of \textit{T. Chase} and \textit{G. Gruenhage} [Topology Appl. 160, No. 1, 45--49 (2013; Zbl 1264.54039)] to follow from monotonic metacompactness. We show that all of the results of that earlier paper that follow from the monotonic covering property follow just from ...
Chase, Timothy, Gruenhage, Gary
openaire   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

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