Results 31 to 40 of about 236,678 (289)
ABSTRACT Neuroblastoma is the most common extracranial solid tumor in early childhood. Its clinical behavior is highly variable, ranging from spontaneous regression to fatal outcome despite intensive treatment. The International Society of Pediatric Oncology Europe Neuroblastoma Group (SIOPEN) Radiology and Nuclear Medicine Specialty Committees ...
Annemieke Littooij +11 more
wiley +1 more source
Uniformities and covering properties for partial frames (I) [PDF]
Partial frames provide a rich context in which to do pointfree structured and unstructured topology. A small collection of axioms of an elementary nature allows one to do much traditional pointfree topology, both on the level of frames or locales, and ...
John Frith, Anneliese Schauerte
doaj
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Uniformities and covering properties for partial frames (II) [PDF]
This paper is a continuation of [Uniformities and covering properties for partial frames (I)], in which we make use of the notion of a partial frame, which is a meet-semilattice in which certain designated subsets are required to have joins, and finite ...
John Frith, Anneliese Schauerte
doaj
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Menger's covering property and groupwise density [PDF]
AbstractWe establish a surprising connection between Menger's classical covering property and Blass-Laflamme's modern combinatorial notion of groupwise density. This connection implies a short proof of the groupwise density bound on the additivity number for Menger's property.
Tsaban, Boaz, Zdomskyy, Lyubomyr
openaire +3 more sources
The role and implications of mammalian cellular circadian entrainment
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Selection principles and bitopological hyperspaces
In this paper we continue to research relationships between closure-type properties of hyperspaces over a space X and covering properties of X. For a Hausdorff space X we denote by 2X the family of all closed subsets of X.
Alexander V. Osipov
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source

