Results 41 to 50 of about 1,281,596 (279)
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Uniformities and covering properties for partial frames (II) [PDF]
Categories and General Algebraic Structures with Applications, 2014 This paper is a continuation of [Uniformities and covering properties for partial frames (I)], in which we make use of the notion of a partial frame, which is a meet-semilattice in which certain designated subsets are required to have joins, and finite ...
John Frith, Anneliese Schauerte
doaj
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Covering theorems for Artinian rings [PDF]
, 1997 The covering properties of Artinian rings which depend on their additive structure only, are ...
Borbély, A. +3 more
core
Menger's covering property and groupwise density [PDF]
Journal of Symbolic Logic, 2006 AbstractWe establish a surprising connection between Menger's classical covering property and Blass-Laflamme's modern combinatorial notion of groupwise density. This connection implies a short proof of the groupwise density bound on the additivity number for Menger's property.
Tsaban, Boaz, Zdomskyy, Lyubomyr
openaire +3 more sources
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Selection principles and bitopological hyperspaces
Applied General Topology, 2023 In this paper we continue to research relationships between closure-type properties of hyperspaces over a space X and covering properties of X. For a Hausdorff space X we denote by 2X the family of all closed subsets of X.
Alexander V. Osipov
doaj +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source