Results 61 to 70 of about 274,570 (306)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Covering properties in countable products, II [PDF]

open access: yes, 2006
summary:In this paper, we discuss covering properties in countable products of Čech-scattered spaces and prove the following: (1) If $Y$ is a perfect subparacompact space and $\{X_n : n\in \omega \}$ is a countable collection of subparacompact Čech ...
Hidenori Tanaka   +3 more
core  

A study of new dimensions for ideal topological spaces

open access: yesApplied General Topology
In this paper new notions of dimensions for ideal topological spaces are inserted, called *-quasi covering dimension and ideal quasi covering dimension.
Fotini Sereti
doaj   +1 more source

On a Covering Property of Convex Sets [PDF]

open access: yesProceedings of the American Mathematical Society, 1976
Let { K 1
openaire   +2 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Covering machines

open access: yes, 1992
We construct 2-state covering machines from binary linear codes with a sufficiently rich subcode structure. The goal is to trade multiple covering properties for increased redundancy.
Calderbank, A.R.
core   +1 more source

On Some Types of Multigranulation Covering Based on Binary Relations

open access: yesJournal of Function Spaces, 2021
Recently, the notions of right and left covering rough sets were constructed by right and left neighborhoods to propose four types of multigranulation covering rough set (MGCRS) models.
Ashraf Nawar, E. A. Elsakhawy
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

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