Results 41 to 50 of about 236,678 (289)

Tailored modular assembly derived self-healing polythioureas with largely tunable properties covering plastics, elastomers and fibers

Nature Communications, 2022
Intrinsic self-healing polymers attract increasing attention but often suffer from a narrow self-healing temperature range and unsatisfactory mechanical performance.
Yan Mei Li, Ze Ping Zhang, Min Zhi Rong, Ming Qiu Zhang   +3 more
doaj   +1 more source

Green synthesis of CdS:Sn NPs by Starch as a Covering Agent and Studying its Physical Properties

مجلة بغداد للعلوم, 2023
The aim of this research is to employ starch as a stabilizing and reducing agent in the production of CdS nanoparticles with less environmental risk, easy scaling, stability, economical feasibility, and suitability for large-scale production ...
zainab yaaqoub, Nada K. Abbas
doaj   +1 more source

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

Novel Models of Fuzzy Rough Coverings Based on Fuzzy α-Neighborhood and its Application to Decision-Making

IEEE Access, 2020
Recently, the concept of a fuzzy $\alpha $ - neighborhood operator with reflexivity was established and a fuzzy rough set covering based on a fuzzy $\alpha $ - neighborhood operator was defined by Zhang et al. As a generalization of Zhang et al. models,
Jue Ma, Mohammed Atef, Ahmed Mostafa Khalil, Nasruddin Hassan, Gui-Xiu Chen   +4 more
doaj   +1 more source

Covering Rough Sets in Terms of Topological Bi-Neighbourhoods and Their Applications

Journal of Mathematics, 2023
Neighbourhoods are one of the important topics in topology that relies on two types of neighbours of a point and has many applications in the graph theory and in the sciences and medical sciences.
Amal T. Abushaaban, Abdelfattah A. El Atik, O. A. Embaby   +2 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

A study of new dimensions for ideal topological spaces

Applied General Topology
In this paper new notions of dimensions for ideal topological spaces are inserted, called *-quasi covering dimension and ideal quasi covering dimension.
Fotini Sereti
doaj   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source