Results 151 to 160 of about 6,194,408 (253)
OAF Blocks SIAH1‐Mediated Degradation of SCPX, a Therapeutic Strategy for MASLD
Advanced Science, EarlyView.This study shows OAF directly binds to SCPX and inhibits its interaction with the E3 ligase SIAH1, thereby protecting SCPX from ubiquitin‐dependent degradation and stabilizing its levels. This OAF‐SCPX axis represents a novel pathway in lipid homeostasis, highlighting OAF as a promising therapeutic candidate for MASLD.
Zongxi Li +11 more
wiley +1 more source
National Forum on COVID-19 Vaccine : finale
The National Forum on COVID-19 Vaccine, a 3-day virtual event, highlighted vaccination efforts at all levels of government, across non-governmental organizations and at the individual level.
core
Advanced Science, EarlyView.Compared to E8, mTeSR1 culture downregulated WNT and TGF‑β signaling, and upregulated neural differentiation pathways, enhancing neural priming. Under skin organoid induction conditions, mTeSR1‑cultured hESCs generated organoids with significantly higher neuroepithelial differentiation.
Zhongliang Chen +7 more
wiley +1 more source
Psychoeducational Challenges of Dyslexic Children During the COVID-19 Pandemic: A Systematic Review. [PDF]
DyslexiaGhasemi SA +3 more
europepmc +1 more source
National Forum on COVID-19 Vaccine : champions
Vaccine champions have an important role in building trust and vaccine confidence and increasing vaccine uptake in their communities. Now that COVID-19 vaccines are available, work must continue to deliver safe, effective, and equitable vaccination to ...
core
Advanced Science, EarlyView.[A&T]MLN is a triple‐modal nanoplatform with siRNA‐loaded LN coated with hybrid ACE2/macrophage membrane. It blocks viral entry, neutralizes IL‐6/IL‐1β/TNF‐α, and delivers siRNA to suppress viral replication. In a murine lung injury model, it attenuates inflammation, offering a multi‐pronged strategy against SARS‐CoV‐2 variants and hyperinflammation ...
Hui Li +19 more
wiley +1 more source
Intelligent Programmable Membrane Nanosponge for Early Virus Blocking
Advanced Science, EarlyView.A smart programmable nanosponge (ACNPs) displays high‐density viral receptors on its membrane and encapsulates fusion inhibitors to capture virions at the infection source through competitive binding and blocks their entry through protease inhibition for ultra‐early cascade interception. This modular, mucus‐penetrating platform shifts antiviral defence
Ze Chen +17 more
wiley +1 more source
Does COVID-19 infection change appetite and dietary habits? [PDF]
Medicine (Baltimore)Alzaben AS +7 more
europepmc +1 more source