Results 151 to 160 of about 5,127,009 (325)

Rational Development of a Novel Emulgel Adjuvant for Single‐Shot Effective Vaccination: A Multivariate Analysis Approach

Advanced Materials, EarlyView.
Using multivariate analysis, a novel emulgel adjuvant is developed by combining key nanoemulsion formulation variables–hydrogel trapping, small globule size, and mannide monooleate surfactant–achieving 10× greater immunogenicity than MF59 in mice after a single shot.
Ahmed O. Shalash, Waleed M. Hussein, Ummey J. Nahar, Jingwen Wang, Lantian Lu, Armira Azuar, Jolynn J. E. Kiong, Prashamsa Koirala, Zeinab G. Khalil, Istvan Toth   +9 more
wiley   +1 more source

Characteristics, risk factors and outcomes among the first consecutive 1096 patients diagnosed with COVID-19 in Kuwait

EClinicalMedicine, 2020
Background: In Kuwait, prior to the first case of COVID-19 being reported in the country, mass screening of incoming travelers from countries with known outbreaks was performed and resulted in the first identified cases in the country. All COVID-19 cases
Sulaiman Almazeedi, Sarah Al-Youha, Mohammad H. Jamal, Mohannad Al-Haddad, Ali Al-Muhaini, Fahad Al-Ghimlas, Salman Al-Sabah   +6 more
doaj  

A ODISSEIA DE UMA ALFABETIZADORA EM TEMPOS DE PANDEMIA DA COVID-19

, 1969
Gabriela Medeiros Nogueira, Janaina Martins Lapuente, Caroline Braga Michel, Juliane de Oliveira Alves Silveira   +3 more
openalex   +2 more sources

Reengineering Endogenous Targeting Lipid Nanoparticles (ENDO) for Systemic Delivery of mRNA to Pancreas

Advanced Materials, EarlyView.
ENDO lipid nanoparticles containing cholecalciferol as a fifth component demonstrate mRNA delivery to the pancreas with 99% selectivity, including beta cells. This platform shows minimal toxicity and sustained protein expression for up to 3 days in a dose‐dependent manner, offering a novel approach to pancreas‐specific mRNA delivery and gene therapy ...
Ivan Isaac, Luv Patel, Nguyen Tran, Amarnath Singam, DongSoo Yun, Prasun Guha, Seungman Park, Chandrabali Bhattacharya   +7 more
wiley   +1 more source

NARRATIVAS DE GESTORES ESCOLARES DE ESCOLAS DO CAMPO EM TEMPO DE PANDEMIA DE COVID-19

, 1969
Darciel Pasinato, Fabiana Regina da Silva, Cristiane Medianeira da Silva Reis   +2 more
openalex   +2 more sources

Advances and Strategies in Enhancing mRNA Cancer Vaccines

Advanced Materials, EarlyView.
Messenger RNA (mRNA) vaccines offer a powerful approach for cancer immunotherapy, but their clinical impact remains limited by delivery challenges and suboptimal immune activation. This review discusses key biological barriers and design strategies—including structural optimization, immunomodulation, organ targeting delivery, and advanced nanocarriers ...
Miao Zhang, Shengqi Chen, Haijun Hu, Yenhui Ong, Qianqian Ni   +4 more
wiley   +1 more source

COPING MECHANISMS AS MEDIATORS IN THE RELATIONSHIP BETWEEN PERCEIVED STRESS AND PRECAUTIONS DURING THE COVID-19 PANDEMIC

, 1970
Ana Genc, Jasmina Pekić, Ilija Milovanović   +2 more
openalex   +2 more sources

Temporal dynamics in viral shedding and transmissibility of COVID-19

Nature Network Boston, 2020
Xi He, E. Lau, P. Wu, Xilong Deng, Jian Wang, Xinxin Hao, Y. Lau, J. Wong, Y. Guan, Xinghua Tan, Xiao-Neng Mo, Yan-qing Chen, B. Liao, Weilie Chen, F. Hu, Qing Zhang, M. Zhong, Yanrong Wu, Ling-Zhai Zhao, Fuchun Zhang, B. Cowling, Fang Li, G. Leung   +22 more
semanticscholar   +1 more source

Artificial Intelligence‐Driven Nanoarchitectonics for Smart Targeted Drug Delivery

Advanced Materials, EarlyView.
This perspective introduces an artificial intelligence (AI)‐driven nanoarchitectonics framework for targeted drug delivery, combining database‐guided nanocarrier design, machine learning (ML)‐assisted surface engineering with a designed targeting system, and in silico modeling for dynamic optimization.
Hayeon Bae, Hyunsub Ji, Konstantin Konstantinov, Ronald Sluyter, Katsuhiko Ariga, Yong Ho Kim, Jung Ho Kim   +6 more
wiley   +1 more source

The anesthesiologist and COVID-19

Brazilian Journal of Anesthesiology (English Edition), 2020
Quintão, Vinícius Caldeira, Simões, Cláudia Marquez, Lima, Laís Helena Navarro e, Barros, Guilherme Antônio Moreira de, Salgado-Filho, Marcello Fonseca, Guimarães, Gabriel Magalhães Nunes, Alves, Rodrigo Leal, Caetano, Ana Maria Menezes, Schmidt, André Prato, Carmona, Maria José Carvalho   +9 more
openaire   +9 more sources