Results 171 to 180 of about 740,744 (261)

Accelerating Primary Screening of USP8 Inhibitors from Drug Repurposing Databases with Tree‐Based Machine Learning

Advanced Intelligent Discovery, EarlyView.
This study introduces a tree‐based machine learning approach to accelerate USP8 inhibitor discovery. The best‐performing model identified 100 high‐confidence repurposable compounds, half already approved or in clinical trials, and uncovered novel scaffolds not previously studied. These findings offer a solid foundation for rapid experimental follow‐up,
Yik Kwong Ng, Sharon Ai Er Lam, Wei Chun Lim, Hannah Hui Min Toh, Shi Jun Ang   +4 more
wiley   +1 more source

Cell-free nucleic acids as a non-invasive biomarker for predicting COVID-19 disease severity and outcome: a retrospective cohort study. [PDF]

BMC Infect Dis
Kubiliute I, Urboniene J, Majauskaite F, Tamasauskas D, Juozapaite D, Jancoriene L.   +5 more
europepmc   +1 more source

Interpretability and Representability of Commutative Algebra, Algebraic Topology, and Topological Spectral Theory for Real‐World Data

Advanced Intelligent Discovery, EarlyView.
This article investigates how persistent homology, persistent Laplacians, and persistent commutative algebra reveal complementary geometric, topological, and algebraic invariants or signatures of real‐world data. By analyzing shapes, synthetic complexes, fullerenes, and biomolecules, the article shows how these mathematical frameworks enhance ...
Yiming Ren, Guo‐Wei Wei
wiley   +1 more source

Comprehensive longitudinal profiling identifies differential frequency, epitope specificity, and effector function of CD8⁺ T-cells across COVID-19 disease severities. [PDF]

EBioMedicine
Amaya Hernandez SP, Munk KK, Danilov K, Kadivar M, Hersby DS, Tamhane T, Stegenborg-Grathwohl SM, Pedersen AG, Gang AO, Hadrup SR, Saini SK.   +10 more
europepmc   +1 more source

Smart Denture with Embedded Thin‐Film Temperature Sensors Patterned by Femtosecond Laser Pulse for Elderly Healthcare

Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.
We demonstrate the direct‐laser patterning of a gold thin film on polymethyl methacrylate to fabricate a temperature sensor for dentures. The temperature sensor‐embedded smart dentures are evaluated in an oral environment, enabling in‐situ monitoring for elderly healthcare.
Han Ku Nam, Yong Kwon Chae, Seoung‐Jin Hong, Younggen Lee, Dongwook Yang, Byunggi Kim, Sang Wook Kang, Young‐Jin Kim   +7 more
wiley   +1 more source

Correction: Yenmis et al. The Distribution of Sport Performance Gene Variations Through COVID-19 Disease Severity. <i>Diagnostics</i> 2025, <i>15</i>, 701. [PDF]

Diagnostics (Basel)
Yenmis G, Kallenci I, Dokur M, Koc S, Yalinkilic SB, Atak E, Demirbilek M, Arkan H.   +7 more
europepmc   +1 more source

Using photovoice to understand community perceptions of firearm risks and protective factors among Asian Americans

American Journal of Community Psychology, EarlyView.
Abstract This study used photovoice methodology to explore Asian Americans' perspectives on the root causes and protective factors of firearm violence in their communities. Photovoice provided a participatory platform for community members to document lived experiences and identify priorities for change.
Tsu‐Yin Wu, Szu‐Hsien Chen, Xining Yang, Ken Resnicow, Hsing‐Fang Hsieh   +4 more
wiley   +1 more source

Euthyroid Sick Syndrome as an Index of Prognosis in Severe COVID-19 Disease. [PDF]

Medicina (Kaunas)
Athanassiou L, Kostoglou-Athanassiou I, Kaiafa G, Nikolakopoulou S, Konstantinou A, Mascha O, Samaras C, Savopoulos C, Shoenfeld Y, Athanassiou P.   +9 more
europepmc   +1 more source

Border harm and affective injustice: The politics of anger at the Melilla border, Spain

American Journal of Community Psychology, EarlyView.
Abstract This article examines protests in a detention center in Melilla, Spain—a site where structural violence intersects with the everyday harms of confinement. Adopting a justice and dignity‐centered perspective, we analyze grassroots forms of resistance emerging at the border. The study focuses on the protests of Tunisian migrants and explores the
Corina Tulbure
wiley   +1 more source

Modelling the dynamically consistent numerical methods for COVID-19 disease with cost effectiveness strategies. [PDF]

Sci Rep
Li S, Abbas MA, Khan IU, Akgül A, Alkhathami AG, Hassani MK.   +5 more
europepmc   +1 more source