Results 61 to 70 of about 740,744 (261)

Hospitalisation and mortality risk of SARS-COV-2 variant omicron sub-lineage BA.2 compared to BA.1 in England

Nature Communications, 2022
In this cohort study, the authors investigate the risk of severe outcomes following infection from Omicron BA.1 and BA.2 sub-lineages. Using whole genome sequencing and electronic health record data for ~980,000 BA.1 and ~250,000 BA.2 cases in England ...
H. H. Webster, T. Nyberg, M. A. Sinnathamby, N. Abdul Aziz, N. Ferguson, G. Seghezzo, P. B. Blomquist, J. Bridgen, M. Chand, N. Groves, R. Myers, R. Hope, E. Ashano, J. Lopez-Bernal, D. De Angelis, G. Dabrera, A. M. Presanis, S. Thelwall   +17 more
doaj   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

The concept of disease in the time of COVID-19 [PDF]

Theoretical Medicine and Bioethics, 2020
AbstractPhilosophers of medicine have formulated different accounts of the concept of disease. Which concept of disease one assumes has implications for what conditions count as diseases and, by extension, who may be regarded as having a disease (disease judgements) and for who may be accorded the social privileges and personal responsibilities ...
Maria Cristina Amoretti, Elisabetta Lalumera   +1 more
openaire   +4 more sources

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

FEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow, Isabel Brandtjen, Yaxin Mo, Melissa Gulley, Louis Osorio, Sagar Kudchodkar, Nandita C. Jhumur, Christine C. Roberts, Lisa K. Denzin, David I. Shreiber, Biju Parekkadan, Hao Lin, Joel N. Maslow   +12 more
wiley   +1 more source

Comparison of SARS-CoV-2 seroprevalence estimates between commercial lab serum specimens and blood donor specimens, United States, September–December 2021

Microbiology Spectrum
We estimated monthly cross-sectional seroprevalence rates of anti-nucleocapsid (anti-N) and anti-spike (anti-S) antibodies to severe acute respiratory syndrome coronavirus 2 in two U.S. nationwide studies. The nationwide blood donor seroprevalence (NBDS)
Szu-Yu Zoe Kao, Elise Nycz, Tina J. Benoit, Kristie E. N. Clarke, Jefferson M. Jones   +4 more
doaj   +1 more source

The first sixty days of COVID-19 in a humanitarian response setting: a descriptive epidemiological analyses of the outbreak in South Sudan

The Pan African Medical Journal, 2020
INTRODUCTION: The coronavirus disease 2019 (COVID-19) was declared a pandemic on March 11, 2020. South Sudan, a low-income and humanitarian response setting, reported its first case of COVID-19 on April 5, 2020.
Joy Luba Lomole Waya, Richard Lako, Sudhir Bunga, Helen Chun, Valerie Mize, Boniface Ambani, Joseph Francis Wamala, Argata Guracha Guyo, John Henry Gray, Malick Gai, Sylvester Maleghemi, Matthew Kol   +11 more
doaj   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

A qualitative assessment of cleaning and hand hygiene practices at shelters serving people experiencing homelessness during the COVID-19 pandemic, Atlanta, GA – May-June, 2020

BMC Public Health
Background Cleaning practices and hand hygiene are important behaviors to prevent and control the spread of infectious disease, especially in congregate settings.
Bethlehem N. Besrat, Emily Mosites, Martha P. Montgomery, Amanda G. Garcia-Williams, Emily Trautner, Kristie E. N. Clarke, Brittany Marshall, Cathryn Vassell, Candace Rutt, Shantrice L. Jones   +9 more
doaj   +1 more source

Validation and clinical evaluation of a SARS-CoV-2 surrogate virus neutralisation test (sVNT)

Emerging Microbes and Infections, 2020
To understand SARS-CoV-2 immunity after natural infection or vaccination, functional assays such as virus neutralising assays are needed. So far, assays to detect SARS-CoV-2 neutralising antibodies rely on cell-culture based infection assays either using
Benjamin Meyer, Johan Reimerink, Giulia Torriani, Fion Brouwer, Gert-Jan Godeke, Sabine Yerly, Marieke Hoogerwerf, Nicolas Vuilleumier, Laurent Kaiser, Isabella Eckerle, Chantal Reusken   +10 more
doaj   +1 more source

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

Aging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho, Quang Le, Ngoc Thach Tran, Van Viet Ung, Loc Vu   +4 more
wiley   +1 more source