Results 131 to 140 of about 299,239 (347)
Possible Old Drugs for Repositioning in COVID-19 Treatment: Combating Cytokine Storms from Haloperidol to Anti-interleukin Agents [PDF]
, 2020 Serkan Tulgar +3 more
openalex +1 more source
Biomaterial Strategies for Targeted Intracellular Delivery to Phagocytes
Advanced Functional Materials, EarlyView.Phagocytes are essential to a functional immune system, and their behavior defines disease outcomes. Engineered particles offer a strategic opportunity to target phagocytes, harnessing inflammatory modulation in disease. By tuning features like size, shape, and surface, these systems can modulate immune responses and improve targeted treatment for a ...
Kaitlyn E. Woodworth +2 more
wiley +1 more source
iScience, 2022 Summary: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the pathogen of coronavirus disease 2019 (COVID-19), has infected hundreds of millions of people and caused millions of deaths.
Jianhua Wang +12 more
doaj
Bioprinted Micro‐Clots for Kinetic Analysis of Endothelial Cell‐Mediated Fibrinolysis
Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.This paper describes the development of a microscale model that quantifies the breakdown of fibrin by endothelial cells. The small size scale of this engineered system enables fibrin breakdown to be observed without the addition of external activators. This system could help in identifying compounds which both promote and hinder thrombosis.
Jonathan J. Chang +5 more
wiley +1 more source
Drugs used for the treatment of COVID-19: A Review
Faridpur Medical College Journal, 2021 COVID-19 is primarily a respiratory disease caused by a newly discovered SARS-CoV-2 virus and identified in the city of Wuhan, China in December 2019. World Health Organization (WHO) has declared this disease as a pandemic, and warned other countries. Presently this has affected 221 countries, areas or territories worldwide, Spreading of this disease ...
openaire +2 more sources
Characteristics of the Coronavirus Disease 2019 and related Therapeutic Options
Molecular Therapy: Methods & Clinical Development, 2020 The coronavirus disease 2019 (COVID-19) is a new type of pneumonia caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection. COVID-19 is affecting millions of patients, and the infected number keeps increasing.
Boxuan Huang +9 more
doaj
Lipid Nanoparticle‐Mediated CRISPR‐Cas13a Delivery for the Control of Bacterial Infection
Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.New formulations of lipid nanoparticles (LNPs) that can deliver nucleic acids to Gram‐negative bacteria are proposed to combat bacterial infection. The delivery of nucleic acids by LNPs is aided by LNP‐helpers which weaken the bacterial outer membrane. LNPs encapsulating the Cas13a/gRNA expression vector achieve an antibacterial effect in both in vivo ...
Bookun Kim +9 more
wiley +1 more source
Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.The top‐performing lipid nanoparticle, incorporating a novel ionizable lipid derived from vitamin B5, demonstrates high mRNA transfection efficiency, low toxicity, favorable stability, targeted delivery to lymphoid tissues, and high immunogenicity, showing promise as a carrier for mRNA vaccines for infectious diseases and cancer.
Soyeon Yoo +11 more
wiley +1 more source
Repurposed GI Drugs in the Treatment of COVID-19 [PDF]
Digestive Diseases and Sciences, 2020 Aguila, Enrik John T., Cua, Ian Homer Y.
openaire +2 more sources
Adverse Drug Reactions During COVID-19 Treatment
Turkish Journal of Pediatric Disease, 2020 Coronavirus disease 2019 (Covid-19) has been widely spread. Although many drugs are used in the treatment of COVID-19, there is still no specific treatment with proven reliability and effectiveness and there are many studies to find effective treatment.
METBULUT, Pınar +1 more
openaire +3 more sources