Results 111 to 120 of about 231,281 (308)

Bafilomycin A1: A potential candidate drug for COVID-19 Treatment

open access: yes, 2022
The crisis of the COVID-19 pandemic around the world has been devastating as many lives have been lost. There is an urgent need for the right therapeutic drug to control the disease.
Kamal Rawal   +3 more
core   +2 more sources

Drug safety of frequently used drugs and substances for self-medication in COVID-19

open access: yesTherapeutic Advances in Drug Safety, 2022
During the COVID-19 pandemic, the behavior of self-medication has increased. The dissemination of misleading information regarding the efficacy of certain drugs or substances for the prevention and treatment of COVID-19 has been the major contributing ...
Daniela Baracaldo-Santamaría   +2 more
doaj   +1 more source

COVID‐19 Vaccination Is Not Associated With the Development of Idiopathic Inflammatory Myositis in US Veterans

open access: yesArthritis Care &Research, EarlyView.
Objective Several case reports have proposed a potential association between COVID‐19 vaccination and the subsequent development of idiopathic inflammatory myositis (IIM). This study examined prior COVID‐19 vaccination in US veterans who developed new‐onset IIM compared to those without new‐onset IIM.
Caleb Hernández   +10 more
wiley   +1 more source

Use of a Molecular Signature Response Classifier to Inform Treatment Selection Improves Clinical Disease Activity Among Patients with Rheumatoid Arthritis Initiating a Biologic or Targeted Synthetic Disease‐Modifying Antirheumatic Drug

open access: yesArthritis Care &Research, EarlyView.
Objective We assessed the effectiveness of PrismRA to improve clinical outcomes among patients with rheumatoid arthritis (RA) initiating treatment with a biologic or targeted synthetic disease‐modifying antirheumatic drug (b/tsDMARD). Methods PrismRA incorporated 19 gene expression features and four clinical features to assess a patient's likelihood of
Fenglong Xie   +3 more
wiley   +1 more source

Signal Amplification by Reversible Exchange for COVID-19 Antiviral Drug Candidates

open access: yes, 2020
Several drug candidates have been proposed and tested as the latest clinical treatment for the coronavirus pneumonia (COVID-19). Chloroquine, hydroxychloroquine, ritonavir/lopinavir, and favipiravir are proved to be effective after treatment.
Sung Keon Namgoong (8648892)   +13 more
core   +1 more source

FAVIPIRAVIR AS A POTENTIAL DRUG IN THE TREATMENT OF COVID-19

open access: yesInternational Journal of Research -GRANTHAALAYAH, 2020
Favipiravir is a drug developed for use against influenza and has been used successfully in other infectious conditions. After being internalized in the cell, the substance is phosphoribosylated acting on the RNA polymerase, and thus inhibiting replication and RNA viruses.
Dany Geraldo Kramer   +6 more
openaire   +3 more sources

High Health Care Utilization Preceding Diagnosis With Juvenile Idiopathic Arthritis

open access: yesArthritis Care &Research, EarlyView.
Objective Although early diagnosis improves long‐term outcomes, patients with juvenile idiopathic arthritis (JIA) often experience prolonged, circuitous paths to diagnosis. To inform diagnostic improvement, we sought to characterize health care utilization in the year preceding diagnosis. Methods We identified 10,021 patients with an incident diagnosis
Anna Costello   +5 more
wiley   +1 more source

Ro5 Bioactivity Lab: Identification of Drug Candidates for COVID-19

open access: yes, 2020
The public health emergency known as the coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has led to a large number of deaths worldwide and major socioeconomic disruption.
Žygimantas, Jočys   +8 more
core   +1 more source

Real‐World Trends in Prenatal Antirheumatic Drug Utilization in Ontario, Canada: A Cross‐Sectional Time‐Series Analysis

open access: yesArthritis Care &Research, EarlyView.
Objective This study aimed to describe real‐world trends in preconception and prenatal use of antirheumatic drugs among pregnant individuals with rheumatic diseases in Ontario, Canada. Methods We conducted a time‐series analysis using repeated cross‐sectional data to examine annual patterns of disease‐modifying antirheumatic drug (DMARD) use among ...
Shenthuraan Tharmarajah   +6 more
wiley   +1 more source

Drug repurposing in the treatment of COVID-19: A review

open access: yes, 2021
The first outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection was in Wuhan, Hubei, China in December 2019 and declared as a pandemic by the World Health Organization.
Vikrant, L. Salode   +2 more
core   +2 more sources

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