Results 101 to 110 of about 69,031,262 (351)

Convalescent Plasma for the Treatment of COVID-19: Perspectives of the National Institutes of Health COVID-19 Treatment Guidelines Panel

open access: yesAnnals of Internal Medicine, 2020
In the United States, the efficacy and safety of convalescent plasma for treating coronavirus disease 2019 (COVID-19) is currently being tested in randomized placebo-controlled clinical trials.
Alice K. Pau   +16 more
semanticscholar   +1 more source

COVID-19: the epidemiology and treatment

open access: yesBritish Journal of Hospital Medicine, 2020
After initially emerging in late 2019, coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has spread rapidly to cause a global pandemic. SARS-CoV-2 is a betacoronavirus that is closely related to severe acute respiratory syndrome coronavirus and Middle East respiratory syndrome coronavirus ...
Liujing, Qu, Jinchun, Li, Hao, Ren
openaire   +2 more sources

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Treatment of patients with severe basic diseases combined with infection of novel coronavirus Omicron variant [PDF]

open access: yesZhenduanxue lilun yu shijian, 2022
Diagnosis and Treatment of COVID-19 from Expert Group of Ruijin Hospital, Shanghai Jiao Tong University School of Medicine
doaj   +1 more source

Favipiravir versus other antiviral or standard of care for COVID-19 treatment: a rapid systematic review and meta-analysis

open access: yesVirology Journal, 2020
Background The COVID-19 causing coronavirus is an enveloped RNA virus that utilizes an enzyme RNA dependent RNA polymerase for its replication. Favipiravir (FVP) triphosphate, a purine nucleoside analog, inhibits that enzyme.
D. Shrestha   +5 more
semanticscholar   +1 more source

A Comprehensive Summary of the Knowledge on COVID-19 Treatment

open access: yesAging and Disease, 2021
Currently, the world is challenged by the coronavirus disease 2019 (COVID-19) pandemic. Epidemiologists and researchers worldwide are invariably trying to understand and combat this precarious new disease.
Yu Peng   +4 more
semanticscholar   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Effective treatment of severe COVID-19 patients with tocilizumab

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2020
Significance In patients with coronavirus disease 2019, a large number of T lymphocytes and mononuclear macrophages are activated, producing cytokines such as interleukin-6 (IL-6), which bind to the IL-6 receptor on the target cells, causing the cytokine
Xiaoling Xu   +12 more
semanticscholar   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Potential Treatment Approaches to SARS-CoV-2 and Evaluation of Drug Carrier Systems in Treatment

open access: yesBezmiâlem Science, 2020
The severe acute respiratory syndrome-coronaviruse-2 (SARSCoV- 2) genome is packaged in a helical nucleocapsid surrounded by a lipid bilayer. The virus envelope contains at least three viral proteins called spike protein (S), membrane protein (M) and ...
Sema ARISOY, Tansel ÇOMOĞLU
doaj   +1 more source

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