Results 111 to 120 of about 69,031,262 (351)
Pharmacogenetics Approach for the Improvement of COVID-19 Treatment
Viruses, 2021 The treatment of coronavirus disease 2019 (COVID-19) has been a challenge. The efficacy of several drugs has been evaluated and variability in drug response has been observed.
I. Fricke-Galindo, R. Falfán-Valencia
semanticscholar +1 more source
Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy
Molecular Oncology, EarlyView.LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir +9 more
wiley +1 more source
The treatment and rehabilitation of a critical COVID‐19 case in China
Clinical Case Reports, 2021 The lung lesions of this COVID‐19 patient were slowly absorbed, and the clinical symptoms with shortness of breath were improved slowly in the recovery period.
Xiangde Zheng +5 more
doaj +1 more source
Alpha lipoic acid: A treatment option for diabetic patients with Covid 19
Health Technology Assessment in Action, 2021 The new coronavirus pneumonia, which first occurred in China in December 2019, has a wide spectrum of symptoms from asymptomatic to very severe involvement and even death.
Hossein Bahrami Moghadam +1 more
doaj +1 more source
Journal of Primary Care & Community Health, 2020 Background: Healthcare workers (HCWs) are faced with an elevated risk of exposure to SARS-COV-2 due to the clinical procedures they perform on COVID-19 patients.
M. Ashinyo +7 more
semanticscholar +1 more source
Surveillance of Antibacterial Usage during the COVID-19 Pandemic in England, 2020 [PDF]
, 2021 Changes in antibacterial prescribing during the COVID-19 pandemic were anticipated given that the clinical features of severe respiratory infection syndrome caused by SARS-CoV-2 mirror bacterial respiratory tract infections. Antibacterial consumption was
Berit Muller-Pebody +10 more
core +1 more source
Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection
FEBS Open Bio, EarlyView.Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow +12 more
wiley +1 more source
Pulmonary MedicineBackground and Objectives. The chest computed tomography (chest CT) has played an important role in the management of COVID-19. Few data on its use in sub-Saharan Africa (SSA) are reported.
Serge Emmanuel Obe -A- Ndzem Holenn +8 more
doaj +1 more source
Viral Coagulopathy in Patients With COVID-19: Treatment and Care
Clinical and applied thrombosis/hemostasis, 2020 COVID-19 has proven to be particularly challenging given the complex pathogenesis of SARS-CoV-2. Early data have demonstrated how the host response to this novel coronavirus leads to the proliferation of pro-inflammatory cytokines, massive endothelial ...
N. Kipshidze +7 more
semanticscholar +1 more source
Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound
FEBS Open Bio, EarlyView.We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda +4 more
wiley +1 more source