Results 161 to 170 of about 1,554,916 (325)
The Changing Unpolitics of Covid‐19 Vaccine Procurement
Politics and GovernancePopulist governments engage in “unpolitics” when the electoral incentives for doing so outweigh the distributive risks from policy failure. Studying the joint procurement of vaccines against Covid-19, I show that a group consisting of mostly populist ...
Henning Deters
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Evolution of a transdisciplinary "One Medicine-One Health" approach to global health education at the University of California, Davis. [PDF]
, 2009 In today's world health events in one nation or geographic area often have repercussions for the health and well-being of populations beyond that region; sometimes even globally.
Clifford, Deana +4 more
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A Modular Vaccine Platform Against SARS‐CoV‐2 Based on Self‐Assembled Protein Nanoparticles
Advanced Science, EarlyView.A modular BP26 nanoparticle vaccine platform incorporating the SpyTag/SpyCatcher system enables high‐density, repetitive antigen display with post‐expression flexibility. Conjugation of the SARS‐CoV‐2 RBD to BP26 nanoparticles elicits strong humoral immunity and confers protection against viral challenge in vivo.
Seojung Lee +6 more
wiley +1 more source
Advanced Science, EarlyView.A microfluidic electrochemical biosensor enables sensitive and specific detection of antibodies associated with vaccine‐induced immune thrombotic thrombocytopenia (VITT) and heparin‐induced thrombocytopenia (HIT). The platform uses two antigen targets— platelet factor 4 (PF4) and cross‐linked‐PF4 (c‐PF4)—and microliter volumes of patient sera to ...
Diana F. Cedillo‐Alcantar +8 more
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Targeting DNA‐LNPs to Endothelial Cells Improves Expression Magnitude, Duration, and Specificity
Advanced Science, EarlyView.Attaching antibodies against endothelial cell surface proteins redirects the delivery and expression of DNA‐lipid nanoparticles to organs of interest. Our targeted nanoparticles enable organ‐selective DNA expression in the endothelium of the lungs, brain, or spleen, providing a therapeutic platform for dozens of endothelial‐centric diseases.
Nicolas Marzolini +24 more
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Risk Management and Healthcare Policy, 2021 Addisu Dabi Wake Nursing Department, College of Health Sciences, Arsi University, Asella, EthiopiaCorrespondence: Addisu Dabi WakeNursing Department, College of Health Sciences, Arsi University, P.O. Box: 193/04, Asella, EthiopiaTel +251 910 2867 66Email
Wake AD
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All‐PEG‐Like Block Copolymers Self‐Assemble into Stealth Nanocarriers for Drug Delivery
Advanced Science, EarlyView.Self‐assembling nanoparticles composed entirely of POEGMA are engineered by exploiting side‐chain–dependent amphiphilicity and tunable thermoresponsive behavior. These single‐material nanocarriers encapsulate diverse hydrophobic drugs with high efficiency, retain therapeutic activity, improve in vivo efficacy, and evade anti‐PEG antibodies.
Parul Sirohi +15 more
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Advanced Science, EarlyView.Low‐affinity antibodies are frequently disregarded in discovery pipelines. This work reports P5‐1C8, a Class 1 SARS‐CoV‐2 antibody with weak trimer binding (KD‐to‐IC50 > 3700‐fold) yet potent neutralization of Omicron JN.1. Structural, biophysical, functional, and coarse‐grained simulations collectively demonstrate that transient inter‐spike IgG ...
Niannian Lv +29 more
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Journal of Multidisciplinary Healthcare, 2022 Gete Berihun,1,* Zebader Walle,2,* Daniel Teshome,3,* Leykun Berhanu,1 Mohammed Derso4 1Department of Environmental Health, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia; 2Department of Public Health, College of ...
Berihun G +4 more
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