Results 161 to 170 of about 5,458,526 (247)

Evolution of the SARS‐CoV‐2 Main Protease Under Fitness Constraints Imposed by Folding Stability and Activity

Proteins: Structure, Function, and Bioinformatics, EarlyView.
ABSTRACT The severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) continues to evolve and diversify, leading to the emergence of immune‐evasive variants and underscoring the need for complementary antiviral strategies targeting conserved viral machinery. In this context, the main protease (Mpro) represents a potential therapeutic target because
David Ferreiro, Miguel Arenas
wiley   +1 more source

Determinants of seasonal influenza and COVID-19 vaccine uptake in high-risk individuals in northern Sweden. [PDF]

Hum Vaccin Immunother
Grape L, Persson W, Sergejev A, Vihtari Hansson S, Gyllencreutz L, Togstad H, Normark J, Johansson Kostenniemi U.   +7 more
europepmc   +1 more source

Early grower perceptions and likely acceptance of RNAi‐based biopesticides in Australia

Pest Management Science, EarlyView.
Individual decisions on the adoption of RNAi‐based biopesticides reflect balance of perceived risks and benefits. Adoption can be facilitated through tailored communication strategies highlighting clear scientific evidence of product efficacy. Abstract BACKGROUND Managing pest resistance while reducing reliance on conventional chemical pesticides ...
Raquel Tardin‐Coelho, Julian Clifton, Peta Ashworth   +2 more
wiley   +1 more source

Improving COVID-19 Vaccine Uptake Among Ethnic Minority Communities in Wales: A Community-Based Approach. [PDF]

Immunol Cell Biol
Talabani B, Hanif S, Ramzan K, Mohammed F, Naseem A, Alauddin E.   +5 more
europepmc   +1 more source

Infection risk in rheumatoid arthritis patients treated with biologic and targeted therapies

Rheumatology &Autoimmunity, EarlyView.
In this context, infections associated with each biologic and targeted drug are summarized to inform the stratification of RA patients, including the characteristics of the susceptible patients and their concomitant therapy. We aim to provide a benefit‐risk analysis for clinical decision, and vital indications for the prevention of highly correlated ...
Lujing Wang, Jieshi Lin, Jie Qian
wiley   +1 more source

COVID-19 Vaccine Effectiveness Among Older Adults.

JAMA Netw Open
Laniece Delaunay C, Mateo-Urdiales A, Pérez-Gimeno G, O'Reilly K, Uras M, Erdwiens A, Mlinaric I, Túri G, Martínez-Baz I, Meijer A, Rodrigues AP, Lazar M, Latorre-Margalef N, Lucaccioni H, Verdasca N, Bella A, Rafael de la Cruz Lopez MA, Kelly E, Enouf V, Tolksdorf K, Puzelli S, Ibáñez Pérez AC, Fitzgerald M, Masse S, Oh DY, Kaczmarek M, Bacci S, Kissling E, VEBIS Primary Care Vaccine Effectiveness Group.   +28 more
europepmc   +1 more source

Examining determinants of COVID-19 vaccine hesitancy and acceptance among Arab university students: A regional scoping review. [PDF]

Hum Vaccin Immunother
Gambescia SF, Tran V, Almoayad F, Aboul-Enein BH.   +3 more
europepmc   +1 more source

Industry 5.0 for Sustainable Healthcare Services: Analyzing the Prospects and Obstacles for the Indian Healthcare System

Sustainable Development, EarlyView.
ABSTRACT The fifth industrial revolution (I5.0), which is based on the utilization of interconnected data for efficient resource usage in meeting human requirements, proposes efficient solutions to resource constraint situations. However, the transition to I5.0 in the health sector is not easy and has to face several obstacles.
Ajay Jha, Dindayal Agrawal, Reena Agarwal, Anupam Saxena, Ashish Dwivedi, Sharfuddin Ahmed Khan   +5 more
wiley   +1 more source

Safety and immunogenicity of an mRNA COVID-19 vaccine administered to adults: A phase 2, randomized, active-controlled trial. [PDF]

Hum Vaccin Immunother
Wong R, Kuznetsova A, Baba E, Ganyani T, Berrè S, Boutet P, Ramanathan R, Douglas D, Mann P, Gaudinski MR.   +9 more
europepmc   +1 more source

Influencer Credibility and Responsible Tourism: A Study of Ecotourists' Economic, Socio‐Cultural, and Environmental Responsible Behaviors in Sarawak

Sustainable Development, EarlyView.
ABSTRACT The tourism sector faces pressing sustainability challenges, especially during crises. The rural communities reliant on ecotourism remain vulnerable, highlighting the need for responsible tourism. This study integrates social cognitive theory (SCT) and the elaboration likelihood model (ELM) to examine how self‐efficacy and outcome expectation ...
Wei Chiang Chan, Chee Hua Chin, Winnie Poh Ming Wong   +2 more
wiley   +1 more source