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COVID-19 is a pandemic of unprecedented proportions in recent human history. Less than 18 months since the onset of the pandemic, there are close to two hundred million confirmed cases and four million deaths worldwide. There have also been massive efforts geared towards finding safe and effective vaccines.
Duduzile Ndwandwe, Charles S Wiysonge
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SummarySince the emergence of COVID-19, caused by the SARS-CoV-2 virus at the end of 2019, there has been an explosion of vaccine development. By 24 September 2020, a staggering number of vaccines (more than 200) had started preclinical development, of which 43 had entered clinical trials, including some approaches that have not previously been ...
Tregoning, J. S. +9 more
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COVID-19 vaccines and vaccine administration [PDF]
This article provides an overview of current COVID-19 vaccines available within the UK, including their mode of action, storage and handling. It outlines the recommendations on priority groups for vaccination and provides insight into the training recommendations for vaccinators.
Gordon, Charlotte +2 more
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COVID-19 Vaccination and The Eye [PDF]
To summarize the current evidence on COVID-19 vaccine-associated ocular adverse events.Narrative literature review.The literature search was conducted in August 2021 using 4 electronic databases: MEDLINE, EMBASE, PubMed, and the Cochrane Database of Systematic Reviews.
Michael T.M. Wang +3 more
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This article is a narrative review of the rapidly moving coronavirus disease 2019 vaccine field with an emphasis on clinical efficacy established in both randomized trials and postmarketing surveillance of clinically available vaccines. We review the major clinical trials that supported authorization for general use of the Janssen (Ad.26.CoV2), Pfizer ...
Hahn, William O., Wiley, Zanthia
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COVID-19 vaccines for children [PDF]
Earlier this month, the US Centers for Disease Control and Prevention (CDC) recommended Pfizer’s COVID-19 messenger RNA (mRNA) vaccine for children between 5 and 11 years of age—that’s 28 million children. Yet surveys show that 42 to 66% of parents of these children are reluctant or opposed to seeking this protection.
Jeffrey S, Gerber, Paul A, Offit
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As of 2022, the global population has access to several mRNA and traditional inactivated vaccines. However, their effectiveness in preventing infection, hospitalization, and COVID-associated mortality in Jordan has yet to be evaluated. The purpose of this observational study was to evaluate the relative effectiveness of three approved vaccines against ...
Mohamed J. Saadh, Saif Aldeen Jaber
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COVID‐19: vaccine’s progress [PDF]
Summary Under the pressure of the COVID‐19 pandemic, vaccines were developed and rolled out into mass vaccination campaigns at incredible speed. What normally takes a decade was worked out within a year. Vaccines were produced along many different platforms ranging from inactivated whole virus vaccines over adenovirus‐vectored ...
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Mandating COVID-19 Vaccines [PDF]
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines hold promise to control the pandemic, and help restore normal social and economic life. The Food and Drug Administration (FDA) has granted emergency use authorization (EUA) for 2 mRNA vaccines and will likely issue full biologics licenses in the coming months.
Gostin, Lawrence O. +2 more
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The Time for COVID-19 Vaccination
The composition and dynamics of viral mutant spectra in infected individuals advise that to avoid selection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) escape mutants, vaccination campaigns for coronavirus disease 2019 (COVID-19) should be launched when disease incidence is low.
Domingo, Esteban, Perales, Celia
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