Results 191 to 200 of about 5,155,633 (254)
Proteoforms in Disease: Biomedical Applications of Top‐Down Proteomics
Mass Spectrometry Reviews, EarlyView.ABSTRACT The proteome is a dynamic landscape of proteoforms arising from genetic mutations, alternative splicing, and post‐translational modifications (PTMs), which collectively drive biological function and disease phenotypes. Mass spectrometry (MS)‐based proteomics has emerged as an essential technique for elucidating this molecular complexity ...
Holden T. Rogers +5 more
wiley +1 more source
Plasmepsins as Antimalarial Drug Targets—Then, Now, and the Future
Medicinal Research Reviews, EarlyView.ABSTRACT Malaria is a devastating disease caused by Plasmodium parasites. Plasmodium parasites express ten cathepsin D‐like aspartyl proteases, called plasmepsins (PMs). These PMs have diverse roles fulfill diverse functions throughout the parasite's lifecycle, though several exhibit functional redundancies. Among them, PMV, PMIV, and PMX are essential
Brad E. Sleebs
wiley +1 more source
Mathematical Methods in the Applied Sciences, EarlyView.ABSTRACT In the present investigation, a mathematical model with vaccination, treatment, and environmental impact under real data is presented. Initially, we present the model without any interventions, followed by an examination of its equilibrium points.
Bashir Al‐Hdaibat +4 more
wiley +1 more source
Neurourology and Urodynamics, EarlyView.ABSTRACT Aims To evaluate the prevalence, clinical course, and risk factors of lower urinary tract symptoms (LUTS) in patients hospitalized with COVID‐19, and to assess associations with comorbidities, disease severity, and vaccination status. Methods We conducted a prospective cohort study of adult patients hospitalized with confirmed COVID‐19, who ...
Julia Duarte de Souza +12 more
wiley +1 more source
Mitigating Health Disparities Through Empathetic Policymaking During Times of Crisis
Public Administration and Development, EarlyView.ABSTRACT The COVID‐19 pandemic greatly exacerbated the existing disparities and inequities in health and healthcare among historically marginalized populations. Today, these impacts still echo. These persistent structured inequities erode the public's trust in government, lead to failure in public policies, and result in worse health consequences ...
Yali Pang +2 more
wiley +1 more source
More than proteins for empty stomachs: Wild meat in the BaTonga food system
People and Nature, EarlyView.Abstract Our paper highlights the limitations of the framework used by many conservation‐focused programmes that incorporate food security objectives. This framework encourages the substitution of wild proteins with domestic proteins by promoting animal farming in communities located near conservation areas.
Muriel Figuié +5 more
wiley +1 more source
Impact of the 2019 Novel Coronavirus Pandemic on Canadian Pediatricians
Pediatric Discovery, EarlyView.The rate of burnout was increased among younger pediatricians with less than 20 years of clinical practice, those who had a high level of perception of COVID‐19 exposure, and those working as front‐line physicians, especially if they had seen 20 or more cases of suspected COVID‐19 infection. ABSTRACT The COVID‐19 pandemic has significantly impacted the
Shaneela Shahid +3 more
wiley +1 more source
CDC's COVID-19 state of vaccine confidence insights report : Quarter 3 Report, January 26, 2023
Date Range: July 1 \u2013 September 30, 2022Summary of the 2nd COVID-19 Vaccine Summary Report: 6 months through 5 yearsThis report consolidates findings and ways public health partners can act on the findings related to COVID-19 vaccines for children 6 ...
core
Muscle fatigue in patients with severe long COVID: A 2‐year follow‐up study
PM&R, EarlyView.Abstract Background Fatigue is recognized as one of the most persistent and debilitating symptoms of long COVID, affecting both functionality and quality of life. However, its long‐term effects, especially beyond the first year after infection, remain poorly understood.
Isabella da Silva Almeida +6 more
wiley +1 more source