Results 191 to 200 of about 288,867 (293)

Polyglycerol‐Based Lipids: A Next‐Generation Alternative to PEG in Lipid Nanoparticles for Advanced Drug Delivery Systems

Macromolecular Rapid Communications, EarlyView.
Linear polyglycerol is proposed as a PEG‐alternative in mRNA‐loaded lipid nanoparticles to limit activation of anti‐PEG antibodies and reduce immunogenicity. Resulting nanoparticles may provide similar gene delivery capabilities, while preventing binding of anti‐PEG antibodies compared to PEGylated counterparts.
Yara Ensminger, Rashmi Rashmi, Michael Karimov, Gideon Nölte, Markus Hafke, Ann‐Cathrin Schmitt, David Díaz‐Oviedo, Johannes Köbberling, Rainer Haag   +8 more
wiley   +1 more source

Retraction: Innovations and Challenges in the Development of COVID-19 Vaccines for a Safer Tomorrow. [PDF]

Cureus
Kumar DS, Prasanth K, Bhandari A, Kumar Jha V, Naveen A, Prasanna M.   +5 more
europepmc   +1 more source

Aliphatic Poly(Carbonate)s with Acid Responsive Release Mechanisms for Micellar Anti‐Tumor Drug Delivery

Macromolecular Rapid Communications, EarlyView.
Micellar systems based on biodegradable aliphatic polycarbonates and acid‐responsive triggers enhance drug solubility, stability, and tumor‐selective release. This review covers micelles with acid‐cleavable drug linkages and those that disassemble via acid‐sensitive functionalities.
Adrian V. Hauck, Lutz Nuhn
wiley   +1 more source

Ethnicity and sub-Saharan African representation in the emergency development of covid-19 vaccines. [PDF]

BMJ Med
Taylor AE, Millard G, Packham A, Semuto Ngabonziza JC, Mambo Muvunyi C, Green CA.   +5 more
europepmc   +1 more source

Radiotherapy and Immune System Interactions Historical Perspectives and Clinical Advancements

Molecular Carcinogenesis, EarlyView.
ABSTRACT Radiotherapy (RT) has evolved significantly since its inception from treating benign conditions to becoming a cornerstone of cancer treatment. This review examines the complex interactions between RT and the immune system, highlighting its diverse effects on various immune cell populations, and exploring emerging strategies to enhance ...
Safiy Yahia, Ayman J. Oweida, Houda Bahig, Daniel Taussky   +3 more
wiley   +1 more source

Perception of COVID-19 vaccines in rheumatology patients. [PDF]

Medicine (Baltimore)
Romero-Bogado L, Steiner M, Andreu-Vázquez C, Thuissard-Vasallo IJ, Cobo-Ibáñez T, de la Cámara-Fernández I, Esteban-Vázquez A, Paredes-Romero MB, Richi-Alberti P, Trives-Folguera L, Vergara-Dangond C, Castañeda E, Acosta-Alfaro AV, Cueva-Nájera G, Sánchez-Díaz R, Puerto-Muñoz E, Muñoz-Fernández S.   +16 more
europepmc   +1 more source

Sex- and Gender-specific Observations and Implications for COVID-19 [PDF]

, 2020
McGregor, Alyson J., Walter, Lauren A.
core  

Diverging Cervical Cancer Burden in Africa in the Context of WHO's Elimination Strategy: Insights From GBD 2023

Med Research, EarlyView.
The study highlights the rising cervical cancer burden in Africa, where rates have increased since 1990. Key challenges include structural health inequalities, low HPV vaccination coverage, and limited screening. Projections suggest a continued increase in incidence, deaths, and DALYs by 2038, diverging further from global trends.
Yedong Huang, Shun Chen, Shiqi Ren, Jingwei Zhao, Ziheng Wang, Zhichao Lu, Weiye Qian, Jian Wang, Ting Zhou, Yifan Wang, Zhixin Jiao, Chenyizhe Yuan, Yucheng Hou, Dong Liu, Zhining Liu, Aimin Xu, Li Liu, Qiaojun Hong, Lin Zhang   +18 more
wiley   +1 more source

Immunogenicity of three-dose COVID-19 vaccines in people living with multiple sclerosis. [PDF]

BMJ Neurol Open
Shawe-Taylor MJ, Greenwood D, He A, Hobbs A, Dowgier G, Penn R, Sanderson T, Stevenson-Leggett P, Bazire J, Harvey R, Champsas D, Sharmin S, Aojula A, Bianchi A, Al-Araji S, Hacohen Y, Yam C, Mohamud S, Christensen R, Moccia M, Crick COVID Serology Pipeline, Legacy Investigators, Libri V, Kassiotis G, Gamblin S, Lewis N, Williams B, Swanton C, Gandhi S, Bauer D, Wu M, Carr E, Wall E, Ciccarelli O.   +33 more
europepmc   +1 more source

Investigating Tuberculosis Dynamics Under Various Control Strategies: A Comprehensive Analysis Using Real Statistical Data

Mathematical Methods in the Applied Sciences, EarlyView.
ABSTRACT In the present investigation, a mathematical model with vaccination, treatment, and environmental impact under real data is presented. Initially, we present the model without any interventions, followed by an examination of its equilibrium points.
Bashir Al‐Hdaibat, Mahmoud H. DarAssi, Irfan Ahmad, Muhammad Altaf Khan, Reem Algethamie   +4 more
wiley   +1 more source