Results 11 to 20 of about 2,154,351 (306)

Efficacy and Safety of Sarilumab in Hospitalized Patients With COVID-19: A Randomized Clinical Trial [PDF]

, 2022
Background: Open-label platform trials and a prospective meta-analysis suggest efficacy of anti–IL-6R therapies in hospitalized patients with COVID-19 receiving corticosteroids.
DiCioccio, A. Thomas, Saggar, Suraj, Herman, Gary A., Sivapalasingam, Sumathi, Aberg, Judith A., Kampman, Wendy, Ferreira, Manuel A., Kosmicki, Jack A., O'Brien, Meagan P., Boyapati, Anita, Criner, Gerard, Hosain, Romana, Labriola-Tompkins, Emily, Musser, Bret J., Akinlade, Bolanle, Brown, Samuel M., Bhore, Rafia, Ng Gong, Michelle, Horowitz, Julie E., Hajizadeh, Negin, Sobieszczyk, Magdalena E., Park, William, Gulabani, Daya, Yancopoulos, George D., Mahmood, Adnan, Lederer, David J., Sperber, Steven J., Weinrich, David M., Stein, David K., Baras, Aris, Giannelou, Angeliki, Menon, Vidya, Somersan-Karakaya, Selin, Purcell, Lisa A., Nivens, Michael C., Parrino, Janie, Kowal, Bari, Waldron, Alpana, Braunstein, Ned, Criner|, Ramesh, Divya   +40 more
core   +1 more source

COVID-19 in Older Individuals Requiring Hospitalization

Infectious Disease Reports, 2022
Older individuals have an increased risk for severe coronavirus disease 2019 (COVID-19) and a higher risk for complications and death. The aim of this study was to investigate the clinical characteristics of older patients admitted with COVID-19 and ...
Petros Ioannou, Despoina Spentzouri, Myrto Konidaki, Michalis Papapanagiotou, Sotiris Tzalis, Ioannis Akoumianakis, Theodosios D. Filippatos, Symeon Panagiotakis, Diamantis P. Kofteridis   +8 more
doaj   +1 more source

Differential neutralization and inhibition of SARS-CoV-2 variants by antibodies elicited by COVID-19 mRNA vaccines

Nature Communications, 2022
Emerging SARS-CoV-2 variants raise concerns on immune evasion. Here, the authors evaluate the neutralization efficiency of COVID-19 mRNA vaccinee sera against representative viruses of 13 WHO-designated SARS-CoV-2 variants of concern/interest.
Li Wang, Markus H. Kainulainen, Nannan Jiang, Han Di, Gaston Bonenfant, Lisa Mills, Michael Currier, Punya Shrivastava-Ranjan, Brenda M. Calderon, Mili Sheth, Brian R. Mann, Jaber Hossain, Xudong Lin, Sandra Lester, Elizabeth A. Pusch, Joyce Jones, Dan Cui, Payel Chatterjee, M. Harley Jenks, Esther K. Morantz, Gloria P. Larson, Masato Hatta, Jennifer L. Harcourt, Azaibi Tamin, Yan Li, Ying Tao, Kun Zhao, Kristine Lacek, Ashley Burroughs, Wei Wang, Malania Wilson, Terianne Wong, So Hee Park, Suxiang Tong, John R. Barnes, Mark W. Tenforde, Wesley H. Self, Nathan I. Shapiro, Matthew C. Exline, D. Clark Files, Kevin W. Gibbs, David N. Hager, Manish Patel, Alison L. Halpin, Laura K. McMullan, Justin S. Lee, Hongjie Xia, Xuping Xie, Pei-Yong Shi, C. Todd Davis, Christina F. Spiropoulou, Natalie J. Thornburg, M. Steven Oberste, Vivien G. Dugan, SSEV Bioinformatics Working Group, David E. Wentworth, Bin Zhou   +56 more
doaj   +1 more source

Erectile Dysfunction and COVID-19: a Case Report

Jurnal Profesi Medika, 2021
Coronavirus Diesease-2019 (COVID-19) infection is suspected to affect the sexual behavior and function. The vascular damage related to COVID-19 can affect the impairment of bed blood vessel of penile and finally make the erectile dysfunction (ED).
Gembong Satria Mahardhika, Nastiti Maharani, Theodore Dharma Tedjamartono, Efriadi Ismail   +3 more
doaj   +1 more source

COVID‐19 and Inequalities* [PDF]

Fiscal Studies, 2020
AbstractThis paper brings together evidence from various data sources and the most recent studies to describe what we know so far about the impacts of the COVID‐19 crisis on inequalities across several key domains of life, including employment and ability to earn, family life and health.
Blundell, Richard, Costa Dias, Monica, Joyce, Robert, Xu, Xiaowei   +3 more
openaire   +4 more sources

Differential impact of quarantine policies for recovered COVID-19 cases in England: a case cohort study of surveillance data, June to December 2020

BMC Public Health, 2022
Background From 12th March 2020, individuals in England were advised to quarantine in their home if a household member tested positive for SARS-CoV-2.
Rachel Merrick, Dimple Chudasama, Joe Flannagan, Ines Campos-Matos, Annabelle Howard, Renu Bindra, O Noël Gill, Gavin Dabrera, Theresa Lamagni   +8 more
doaj   +1 more source

COVID-19 vaccination for people with disabilities

, 2021
Internationally, people with disabilities have been disproportionately impacted by COVID-19, accounting for nearly 60% of COVID-19 deaths in the UK and overall higher mortality rates based on social, clinical, and demographic factors.
Stall, Nathan M, Brown, H, Katz, G, Bell, S, Rochon, P, Razak, Fahad, Lunsky, Y, Safar, Y, Downer, Matthew B, Brown, Hilary, Campanella, Sabrina, Cooper, Jane, Porch, W, Rotenberg, Sara, Rochon, Paula A, Downer, Mathew Bruce, Stall, N, Razak, F, Schull, M, Porch, Wendy, Bell, Sandi, Schull, Michael, Safar, Yousef, Lunsky, Yona, Katz, Gabrielle M, Cooper, J, Campanella, S   +26 more
core   +1 more source

Reducing travel-related SARS-CoV-2 transmission with layered mitigation measures: symptom monitoring, quarantine, and testing

BMC Medicine, 2021
Background Balancing the control of SARS-CoV-2 transmission with the resumption of travel is a global priority. Current recommendations include mitigation measures before, during, and after travel.
Michael A. Johansson, Hannah Wolford, Prabasaj Paul, Pamela S. Diaz, Tai-Ho Chen, Clive M. Brown, Martin S. Cetron, Francisco Alvarado-Ramy   +7 more
doaj   +1 more source

Stress Cardiomyopathy in COVID-19 Disease

European Journal of Case Reports in Internal Medicine, 2020
Patients affected by COVID-19 pneumonia may develop stress cardiomyopathy, also known as Takotsubo syndrome (TTS), at different stages during the disease and with different degrees of left ventricular dysfunction.
Maria Cristina Pasqualetto, Eleonora Secco, Manuele Nizzetto, Moreno Scevola, Lorella Altafini, Alberto Cester, Fausto Rigo   +6 more
doaj   +1 more source

Performance of existing and novel surveillance case definitions for COVID-19 in household contacts of PCR-confirmed COVID-19

BMC Public Health, 2021
Background Optimized symptom-based COVID-19 case definitions that guide public health surveillance and individual patient management in the community may assist pandemic control. Methods We assessed diagnostic performance of existing cases definitions (e.
Hannah E. Reses, Mark Fajans, Scott H. Lee, Charles M. Heilig, Victoria T. Chu, Natalie J. Thornburg, Kim Christensen, Sanjib Bhattacharyya, Alicia Fry, Aron J. Hall, Jacqueline E. Tate, Hannah L. Kirking, Scott A. Nabity, The U.S. COVID-19 Household Investigation Team   +13 more
doaj   +1 more source