Results 81 to 90 of about 7,135,840 (226)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Critical Care Ultrasonography and Its Application for COVID-19 [PDF]

open access: yes, 2020
Ultrasound has developed as an invaluable tool in diagnosis and proper management in the intensive care unit (ICU). Application of critical care ultrasonography is quite distinct from the routine comprehensive diagnostic ultrasound exam, because the ...
Chong, MD, Weelic   +4 more
core   +1 more source

The socio-economic implications of the coronavirus pandemic (COVID-19): A review

open access: yesInternational Journal of Surgery, 2020
The COVID-19 pandemic has resulted in over 1.4 million confirmed cases and over 83,000 deaths globally. It has also sparked fears of an impending economic crisis and recession.
Maria Nicola   +7 more
semanticscholar   +1 more source

CoViD-19 Susceptibility [PDF]

open access: yesBioinformation, 2020
There have been over five million cases of infection with the second Corona virus to induce SARS (SARS-CoV2) and close to half a million deaths worldwide since the first report of Corona Virus Disease in late December 2019 (CoViD-19). Over two million CoViD-19 patients have recovered.
openaire   +2 more sources

COVID-19 Vaccines

open access: yesInfectious Disease Clinics of North America, 2022
This article is a narrative review of the rapidly moving coronavirus disease 2019 vaccine field with an emphasis on clinical efficacy established in both randomized trials and postmarketing surveillance of clinically available vaccines. We review the major clinical trials that supported authorization for general use of the Janssen (Ad.26.CoV2), Pfizer ...
Hahn, William O., Wiley, Zanthia
openaire   +3 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

COVID-19 [PDF]

open access: yesDer Nephrologe, 2021
Erley, Christiane   +2 more
openaire   +5 more sources

Case Report: Successful Treatment of a Child With COVID-19 Reinfection-Induced Fulminant Myocarditis by Cytokine-Adsorbing oXiris® Hemofilter Continuous Veno-Venous Hemofiltration and Extracorporeal Membrane Oxygenation

open access: yesFrontiers in Pediatrics, 2022
BackgroundIndirect cardiomyocyte damage-related hyperinflammatory response is one of the key mechanisms in COVID-19-induced fulminant myocarditis. In addition to the clinical benefit of using cytokines absorption hemofiltration, the effectiveness of ...
Phuc H. Phan   +8 more
doaj   +1 more source

Are We #StayingHome to Flatten the Curve? [PDF]

open access: yes, 2020
The recent spread of COVID-19 across the U.S. led to concerted efforts by states to ``flatten the curve" through the adoption of stay-at-home mandates that encourage individuals to reduce travel and maintain social distance.
Sears, James   +3 more
core  

Dysregulation of immune response in patients with COVID-19 in Wuhan, China

open access: yesClinical Infectious Diseases, 2020
Background In December 2019, coronavirus disease 2019 (COVID-19) emerged in Wuhan and rapidly spread throughout China. Methods Demographic and clinical data of all confirmed cases with COVID-19 on admission at Tongji Hospital from January 10 to February ...
C. Qin   +10 more
semanticscholar   +1 more source

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