Results 81 to 90 of about 2,154,351 (306)

Laboratory organisation and management of SARS-CoV-2 infection in Niger, West Africa

open access: yesAfrican Journal of Laboratory Medicine, 2020
Background: As the coronavirus disease 2019 (COVID-19) pandemic unfolds, laboratory services have been identified as key to its containment.
Abdourahamane Yacouba   +14 more
doaj   +1 more source

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao   +6 more
wiley   +1 more source

Is COVID-19 to Blame?

open access: yesCell journal, 2020
Mankind is witnessing economic uncertainty due to a health crisis as never before. In the era of industrialization where the emergence of invisible enemies of humans is causing a great death toll, "nothing seems more universal than health", the old proverb in nearly all human cultures is once again rebirthed by the current COVID-19 pandemic ...
openaire   +3 more sources

Corticosteroid therapy in patients with heart failure hospitalized for COVID-19: a multicenter retrospective study.

open access: yes, 2021
The efficacy of corticosteroid use in COVID-19 has been widely debated [1]. Although corticosteroids were found to be associated with improved clinical outcomes in severely ill patients in a recent systematic review and meta-analysis of randomized ...
Sanz-Canovas, Jaime   +7 more
core   +1 more source

Sex Representation in US Stroke Clinical Trials: A Decade of Trends and Challenges

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stroke remains a major cause of disability and mortality in the US, with significant sex‐based disparities, and females remain underrepresented in stroke clinical trials. We aimed to examine sex representation in US‐based stroke clinical trials, identify trial characteristics associated with higher female enrollment (≥ 50%), and ...
Chaitali Dagli   +5 more
wiley   +1 more source

COVID-19 and Bangladesh

open access: yes
COVID-19 and Bangladesh analyzes the aftermath of the COVID-19 pandemic and features the socioeconomic fallouts for disadvantaged communities in Bangladesh, their coping mechanisms, and implications for the country’s development ambitions.

core   +1 more source

Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Multiple Sclerosis Relapse Activity After Ozanimod Discontinuation in DAYBREAK Trial Participants. ABSTRACT Objective Return of disease activity is expected when patients discontinue disease‐modifying therapy (DMT) for multiple sclerosis (MS). Some MS DMTs are associated with higher‐than‐expected disease activity (rebound) after discontinuation.
Ralf Gold   +12 more
wiley   +1 more source

Tocilizumab, an Exploratory Treatment for Severe COVID-19 Patients

open access: yesCanadian Journal of Infectious Diseases and Medical Microbiology, 2022
The coronavirus disease 2019 (COVID-19) may cause cytokine storm and respiratory illness such as pneumonia and progressive respiratory failure. Tocilizumab (TCZ), a monoclonal antibody that targets the interleukin-6 (IL-6) receptor, was approved as an ...
Yong Wang, Yongfeng Chen, Xiangdong Zhou
doaj   +1 more source

Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi   +8 more
wiley   +1 more source

Expert Report for the UK Covid-19 Public Inquiry: Module 2B: Welsh Government core political and administrative decision-making in relation to the Covid-19 pandemic [PDF]

open access: yes
Expect Report for the UK Covid-19 Public Inquiry: Module 2B: Welsh Government core political and administrative decision-making in relation to the Covid-19 ...
Wincott, Daniel   +1 more
core  

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