Results 41 to 50 of about 21,030 (193)

Ticks Infesting Dogs in Khyber Pakhtunkhwa, Pakistan: Detailed Epidemiological and Molecular Report

open access: yesPathogens, 2023
Ticks and tick-borne diseases are considered a major challenge for human and animal health in tropical, sub-tropical, and temperate regions of the world. However, only scarce information is available on the characterization of tick species infesting dogs
Jehan Zeb   +9 more
doaj   +1 more source

Taenia laticollis and a potentially novel Taenia species from the Eurasian lynx (Lynx) in Northwestern China

open access: yesInternational Journal for Parasitology: Parasites and Wildlife, 2021
The Eurasian lynx (Lynx) is a medium-sized wild cat species distributed throughout Eurasia. There has been no report on Taenia species (Cestoda: Cyclophyllidea) infecting this felid in China. In this study, 24 tapeworms were found in two Eurasian lynxes (
Gang Liu   +7 more
doaj   +1 more source

Comparison and complete mitogenomes of two morphologically similar but ecologically different tick species, Ixodes arboricola and Ixodes lividus (subgenus Pholeoixodes)

open access: yesTicks and Tick-Borne Diseases
Ixodes arboricola and Ixodes lividus are ornithophilic tick species. The former is typically associated with tree-hole dwelling birds, while the latter is a host-specific parasite of sand martins (Riparia riparia).
Sándor Hornok   +8 more
doaj   +1 more source

Revision of the species composition and distribution of Turkish sand flies using DNA barcodes

open access: yesParasites & Vectors, 2019
Background Currently, knowledge regarding the phlebotomine sand fly (Diptera: Psychodidae) fauna of Turkey is restricted to regions with endemic leishmaniasis.
Ozge Erisoz Kasap   +4 more
doaj   +1 more source

Lactate‐Driven Restriction of Mitochondrial Permeability Transition Promotes Resistance to Chemo‐Immunotherapy by Suppressing Tumor PANoptosis

open access: yesAdvanced Science, EarlyView.
Tumor‐derived lactate establishes a metabolic lock that drives chemo‐immunotherapy resistance by suppressing PANoptosis. Mechanistically, KAT8 lactylates the mitochondrial translocator ANT2, which recruits PGAM5 to dephosphorylate CypD. This cascade restricts mitochondrial permeability transition pore opening, preventing pro‐inflammatory mtDNA leakage.
Sen Zhong   +20 more
wiley   +1 more source

Coa3 and Cox14 are essential for negative feedback regulation of COX1 translation in mitochondria [PDF]

open access: yesJournal of Cell Biology, 2010
Regulation of eukaryotic cytochrome oxidase assembly occurs at the level of Cox1 translation, its central mitochondria-encoded subunit. Translation of COX1 messenger RNA is coupled to complex assembly in a negative feedback loop: the translational activator Mss51 is thought to be sequestered to assembly intermediates, rendering it incompetent to ...
Mick, David U.   +6 more
openaire   +5 more sources

Cryptic species Hydatigera kamiyai and other taeniid metacestodes in the populations of small mammals in Serbia

open access: yesParasites & Vectors, 2023
Background Hydatigera (Cestoda: Taeniidae) is a recently resurrected genus with the description of a new species, Hydatigera kamiyai, a cryptic entity within the Hydatigera taeniaeformis species complex.
Milan Miljević   +6 more
doaj   +1 more source

Dual‐line Genome‐scale CRISPR Screening Enables Robust Target Gene Discovery

open access: yesAdvanced Science, EarlyView.
A species‐optimized CRISPR platform integrates efficient piggyBac delivery, genome‐scale sgRNA libraries, and parallel screening in two independently engineered Bactrocera dorsalis Cas9 cell lines. Cross‐line consensus analysis filters line‐specific effects, enriches candidates with reproducible in vivo phenotypes, and reveals conserved, species ...
Ziniu Li   +9 more
wiley   +1 more source

CDK4/MERCs/PINK1 Axis Drives PFOA/HFPO‐TA‐Induced Cardiac Senescence via Mitophagy Defect and cGAS‐STING Activation: In Vitro Amelioration by Cycloastragenol

open access: yesAdvanced Science, EarlyView.
The present study demonstrated that PFOA and HFPO‐TA exposure suppressed CDK4, disrupted MERCs and impaired PINK1/Parkin‐mediated mitophagy, thereby accelerating cardiac senescence, whereas CAG effectively reversed these pathological changes in vitro. Our findings identify CDK4 as a critical regulator bridging mitophagy defects and cardiac senescence ...
Nuo‐Wa Li   +6 more
wiley   +1 more source

Morphometric and Molecular Characterization of Fasciola spp. in Livestock From Northwestern Provinces of Iran

open access: yesVeterinary Medicine and Science
Background Liver flukes from the genus Fasciola are the causative agents for human and livestock fascioliasis. Accurate identification of Fasciola spp. is essential to understanding the epidemiology of fascioliasis.
Hossein Galavani   +4 more
doaj   +1 more source

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