18S-NemaBase: Curated 18S rRNA Database of Nematode Sequences [PDF]
Nematodes are the most abundant and diverse animals on the planet but lack representation in biodiversity research. This presents a problem for studying nematode diversity, particularly when molecular tools (i.e., barcoding and metabarcoding) rely on ...
Gattoni Kaitlin +8 more
doaj +5 more sources
Regulation of translation by methylation multiplicity of 18S rRNA [PDF]
Summary: N6-methyladenosine (m6A) is a conserved ribonucleoside modification that regulates many facets of RNA metabolism. Using quantitative mass spectrometry, we find that the universally conserved tandem adenosines at the 3′ end of 18S rRNA, thought ...
Kuanqing Liu +6 more
doaj +4 more sources
Summary: 18S non-functional rRNA decay (NRD) eliminates non-functional 18S rRNA with deleterious mutations in the decoding center. Dissociation of the non-functional 80S ribosome into 40S and 60S subunits is a prerequisite step for degradation of the non-
Takato Sugiyama +6 more
doaj +4 more sources
pr2-primers: an 18S rRNA primer database for protists
Metabarcoding of microbial eukaryotes (collectively known as protists) has developed tremendously in the last decade, almost uniquely relying on the 18S rRNA gene.
D. Vaulot, S. Geisen, F. Mahé, D. Bass
semanticscholar +7 more sources
metaPR2 : A database of eukaryotic 18S rRNA metabarcodes with an emphasis on protists. [PDF]
In recent years, metabarcoding has become the method of choice for investigating the composition and assembly of microbial eukaryotic communities, and an increasing number of environmental datasets are being published. Although unprocessed sequence files
Vaulot D +6 more
europepmc +2 more sources
Arabidopsis HOT3/eIF5B1 constrains rRNA RNAi by facilitating 18S rRNA maturation. [PDF]
Ribosome biogenesis is essential for protein synthesis in gene expression. Yeast eIF5B has been shown biochemically to facilitate 18S ribosomal RNA (rRNA) 3′ end maturation during late-stage 40S ribosomal subunit assembly and gate the transition from translation initiation to elongation.
Hang R +6 more
europepmc +5 more sources
METTL5-mediated 18S rRNA m6A modification promotes oncogenic mRNA translation and intrahepatic cholangiocarcinoma progression. [PDF]
Intrahepatic cholangiocarcinoma (ICC) is a deadly cancer with rapid tumor progression. While hyperactive mRNA translation caused by mis-regulated mRNA or tRNA modifications promotes ICC development, the role of rRNA modifications remains elusive.
Dai Z +12 more
europepmc +2 more sources
18S rRNA methyltransferases DIMT1 and BUD23 drive intergenerational hormesis. [PDF]
Heritable non-genetic information can regulate a variety of complex phenotypes. However, what specific non-genetic cues are transmitted from parents to their descendants are poorly understood. Here, we perform metabolic methyl-labeling experiments to track the heritable transmission of methylation from ancestors to their descendants in the nematode ...
Liberman N +15 more
europepmc +4 more sources
Taxonomic resolutions based on 18S rRNA genes: a case study of subclass copepoda. [PDF]
Biodiversity studies are commonly conducted using 18S rRNA genes. In this study, we compared the inter-species divergence of variable regions (V1-9) within the copepod 18S rRNA gene, and tested their taxonomic resolutions at different taxonomic levels ...
Shu Wu, Jie Xiong, Yuhe Yu
doaj +2 more sources
Poly(G)7 box: a functional element of mammalian 18S rRNA involved in translation [PDF]
In eukaryotes, the ribosomal small subunit (40S) is composed of 18S rRNA and 33 ribosomal proteins. 18S rRNA has a special secondary structure and is an indispensable part of the translation process.
Dahao Wei +4 more
doaj +2 more sources

