Results 1 to 10 of about 300,369 (293)

18S-NemaBase: Curated 18S rRNA Database of Nematode Sequences [PDF]

open access: yesJournal of Nematology, 2023
Nematodes are the most abundant and diverse animals on the planet but lack representation in biodiversity research. This presents a problem for studying nematode diversity, particularly when molecular tools (i.e., barcoding and metabarcoding) rely on ...
Gattoni Kaitlin   +8 more
doaj   +5 more sources

Regulation of translation by methylation multiplicity of 18S rRNA [PDF]

open access: yesCell Reports, 2021
Summary: N6-methyladenosine (m6A) is a conserved ribonucleoside modification that regulates many facets of RNA metabolism. Using quantitative mass spectrometry, we find that the universally conserved tandem adenosines at the 3′ end of 18S rRNA, thought ...
Kuanqing Liu   +6 more
doaj   +4 more sources

pr2-primers: an 18S rRNA primer database for protists

open access: yesMolecular Ecology Resources, 2021
Metabarcoding of microbial eukaryotes (collectively known as protists) has developed tremendously in the last decade, almost uniquely relying on the 18S rRNA gene.
D. Vaulot, S. Geisen, F. Mahé, D. Bass
semanticscholar   +7 more sources

N6-methyladenosine modification in 18S rRNA promotes tumorigenesis and chemoresistance via HSF4b/HSP90B1/mutant p53 axis

open access: yesCell Chemical Biology, 2023
Aberrant N6-methyladenosine (m6A) modification on mRNA is correlated with cancer progression. However, the role of m6A on ribosomal RNA (rRNA) in cancer remains poorly understood.
Hao Peng
exaly   +2 more sources

Detection of fungal 18S rRNA sequences in conjunction with marine nematode 18S rRNA amplicons [PDF]

open access: yesAquatic Biology, 2009
Free-living nematodes constitute an important component of estuarine and marine benthic ecosystems. Some marine and soil nematodes are known to harbor microbes, including sym- biotic bacteria and fungi, in their external cuticle as well as internally.
Punyasloke Bhadury, David Bilton
exaly   +4 more sources

metaPR2 : A database of eukaryotic 18S rRNA metabarcodes with an emphasis on protists. [PDF]

open access: yesMol Ecol Resour, 2022
In recent years, metabarcoding has become the method of choice for investigating the composition and assembly of microbial eukaryotic communities, and an increasing number of environmental datasets are being published. Although unprocessed sequence files
Vaulot D   +6 more
europepmc   +2 more sources

Sequential Ubiquitination of Ribosomal Protein uS3 Triggers the Degradation of Non-functional 18S rRNA

open access: yesCell Reports, 2019
Summary: 18S non-functional rRNA decay (NRD) eliminates non-functional 18S rRNA with deleterious mutations in the decoding center. Dissociation of the non-functional 80S ribosome into 40S and 60S subunits is a prerequisite step for degradation of the non-
Takato Sugiyama   +6 more
doaj   +2 more sources

METTL5-mediated 18S rRNA m<sup>6</sup>A modification promotes oncogenic mRNA translation and intrahepatic cholangiocarcinoma progression. [PDF]

open access: yesMol Ther, 2023
Intrahepatic cholangiocarcinoma (ICC) is a deadly cancer with rapid tumor progression. While hyperactive mRNA translation caused by mis-regulated mRNA or tRNA modifications promotes ICC development, the role of rRNA modifications remains elusive.
Dai Z   +12 more
europepmc   +2 more sources

The human 18S rRNA m6A methyltransferase METTL5 is stabilized by TRMT112 [PDF]

open access: yesNucleic Acids Research, 2019
N6-methyladenosine (m6A) has recently been found abundantly on messenger RNA and shown to regulate most steps of mRNA metabolism. Several important m6A methyltransferases have been described functionally and structurally, but the enzymes responsible for ...
Nhan van Tran   +10 more
semanticscholar   +6 more sources

Arabidopsis HOT3/eIF5B1 constrains rRNA RNAi by facilitating 18S rRNA maturation. [PDF]

open access: yesProc Natl Acad Sci U S A, 2023
Ribosome biogenesis is essential for protein synthesis in gene expression. Yeast eIF5B has been shown biochemically to facilitate 18S ribosomal RNA (rRNA) 3′ end maturation during late-stage 40S ribosomal subunit assembly and gate the transition from translation initiation to elongation.
Hang R   +6 more
europepmc   +5 more sources

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