Results 11 to 20 of about 309,135 (337)

pr2-primers: an 18S rRNA primer database for protists

Molecular Ecology Resources, 2021
Abstract Metabarcoding of microbial eukaryotes (collectively known as protists ) has developed tremendously in the last decade, almost uniquely relying on the 18S rRNA gene. As microbial eukaryotes are extremely diverse, many primers and primer pairs have been developed.
Daniel Vaulot, Stefan Geisen, Frédéric Mahé, David Bass   +3 more
openaire   +7 more sources

Sequential Ubiquitination of Ribosomal Protein uS3 Triggers the Degradation of Non-functional 18S rRNA

Cell Reports, 2019
Summary: 18S non-functional rRNA decay (NRD) eliminates non-functional 18S rRNA with deleterious mutations in the decoding center. Dissociation of the non-functional 80S ribosome into 40S and 60S subunits is a prerequisite step for degradation of the non-
Takato Sugiyama, Sihan Li, Misaki Kato, Ken Ikeuchi, Atsushi Ichimura, Yoshitaka Matsuo, Toshifumi Inada   +6 more
doaj   +2 more sources

The human 18S rRNA m6A methyltransferase METTL5 is stabilized by TRMT112 [PDF]

Nucleic Acids Research, 2019
Abstract N6-methyladenosine (m6A) has recently been found abundantly on messenger RNA and shown to regulate most steps of mRNA metabolism. Several important m6A methyltransferases have been described functionally and structurally, but the enzymes responsible for installing one m6A residue on each subunit of human ribosomes at ...
Nhan van Tran, Felix G M Ernst, Ben R Hawley, Christiane Zorbas, Nathalie Ulryck, Philipp Hackert, Katherine E Bohnsack, Markus T Bohnsack, Samie R Jaffrey, Marc Graille, Denis L J Lafontaine   +10 more
openaire   +6 more sources

The 5′ end of the 18S rRNA can be positioned from within the mature rRNA [PDF]

RNA, 1999
In yeast, the 5' end of the mature 18S rRNA is generated by endonucleolytic cleavage at site A1, the position of which is specified by two distinct signals. An evolutionarily conserved sequence immediately upstream of the cleavage site has previously been shown to constitute one of these signals.
Sharma, K, Venema, J, Tollervey, D
core   +6 more sources

Taxonomic resolutions based on 18S rRNA genes: a case study of subclass copepoda. [PDF]

PLoS ONE, 2015
Biodiversity studies are commonly conducted using 18S rRNA genes. In this study, we compared the inter-species divergence of variable regions (V1-9) within the copepod 18S rRNA gene, and tested their taxonomic resolutions at different taxonomic levels ...
Shu Wu, Jie Xiong, Yuhe Yu
doaj   +2 more sources

Nop9 binds the central pseudoknot region of 18S rRNA

Nucleic Acids Research, 2017
The assembly of eukaryotic ribosomes requires numerous factors that transiently associate with evolving pre-ribosomal particles. The Pumilio repeat-containing protein Nop9 briefly associates with the 90S pre-ribosome during its co-transcriptional assembly. Here, we show that Nop9 specifically binds an 11-nucleotide sequence of 18S rRNA that forms the 3΄
Bing Wang, Keqiong Ye
openaire   +3 more sources

Identification of a new ribose methylation in the 18S rRNA of S. cerevisiae [PDF]

Nucleic Acids Research, 2015
Methylation of ribose sugars at the 2'-OH group is one of the major chemical modifications in rRNA, and is catalyzed by snoRNA directed C/D box snoRNPs. Previous biochemical and computational analyses of the C/D box snoRNAs have identified and mapped a large number of 2'-OH ribose methylations in rRNAs.
Yang, Jun, Sharma, Sunny, Kötter, Peter, Entian, Karl-Dieter   +3 more
openaire   +4 more sources

metaPR² : A database of eukaryotic 18S rRNA metabarcodes with an emphasis on protists. [PDF]

Mol Ecol Resour, 2022
In recent years, metabarcoding has become the method of choice for investigating the composition and assembly of microbial eukaryotic communities, and an increasing number of environmental datasets are being published. Although unprocessed sequence files
Vaulot D, Sim CWH, Ong D, Teo B, Biwer C, Jamy M, Lopes Dos Santos A.   +6 more
europepmc   +2 more sources

METTL5-mediated 18S rRNA m⁶A modification promotes oncogenic mRNA translation and intrahepatic cholangiocarcinoma progression. [PDF]

Mol Ther, 2023
Intrahepatic cholangiocarcinoma (ICC) is a deadly cancer with rapid tumor progression. While hyperactive mRNA translation caused by mis-regulated mRNA or tRNA modifications promotes ICC development, the role of rRNA modifications remains elusive.
Dai Z, Zhu W, Hou Y, Zhang X, Ren X, Lei K, Liao J, Liu H, Chen Z, Peng S, Li S, Lin S, Kuang M.   +12 more
europepmc   +2 more sources

Towards quantitative metabarcoding of eukaryotic plankton: an approach to improve 18S rRNA gene copy number bias

Metabarcoding and Metagenomics, 2022
Plankton metabarcoding is increasingly implemented in marine ecosystem assessments and is more cost-efficient and less time-consuming than monitoring based on microscopy (morphological).
Jon Lapeyra Martin, Ioulia Santi, P. Pitta, U. John, N. Gypens   +4 more
semanticscholar   +1 more source