Results 11 to 20 of about 346,435 (241)

N6-methyladenosine modification in 18S rRNA promotes tumorigenesis and chemoresistance via HSF4b/HSP90B1/mutant p53 axis.

Cell Chemical Biology, 2023
Aberrant N6-methyladenosine (m6A) modification on mRNA is correlated with cancer progression. However, the role of m6A on ribosomal RNA (rRNA) in cancer remains poorly understood.
Binbin Chen, Ying Huang, Shuiqing He, YU Peng, Lirong Wu, Hao Peng   +5 more
semanticscholar   +3 more sources

Retrieval of a million high-quality, full-length microbial 16S and 18S rRNA gene sequences without primer bias

Nature Biotechnology, 2018
Small subunit ribosomal RNA (SSU rRNA) genes, 16S in bacteria and 18S in eukaryotes, have been the standard phylogenetic markers used to characterize microbial diversity and evolution for decades.
S. Karst, M. Dueholm, S. McIlroy, R. Kirkegaard, P. Nielsen, M. Albertsen   +5 more
semanticscholar   +3 more sources

Nop9 binds the central pseudoknot region of 18S rRNA

Nucleic Acids Research, 2017
The assembly of eukaryotic ribosomes requires numerous factors that transiently associate with evolving pre-ribosomal particles. The Pumilio repeat-containing protein Nop9 briefly associates with the 90S pre-ribosome during its co-transcriptional ...
B. Wang, K. Ye
semanticscholar   +3 more sources

Overexpression of 18S rRNA methyltransferase CrBUD23 enhances biomass and lutein content in Chlamydomonas reinhardtii [PDF]

Frontiers in Bioengineering and Biotechnology, 2023
Post-transcriptional modification of nucleic acids including transfer RNA (tRNA), ribosomal RNA (rRNA) and messenger RNA (mRNA) is vital for fine-tunning of mRNA translation. Methylation is one of the most widespread post-transcriptional modifications in
Chenglong Liu, Chenglong Liu, Haoze Guo, Xinmei Zhao, Bingxi Zou, Ting Sun, Jinwei Feng, Zhiyong Zeng, Xueer Wen, Jun Chen, Zhangli Hu, Sulin Lou, Hui Li   +12 more
doaj   +2 more sources

Thermophile 90S Pre-ribosome Structures Reveal the Reverse Order of Co-transcriptional 18S rRNA Subdomain Integration.

Molecular Cell, 2019
Eukaryotic ribosome biogenesis involves RNA folding and processing that depend on assembly factors and small nucleolar RNAs (snoRNAs). The 90S (SSU-processome) is the earliest pre-ribosome structurally analyzed, which was suggested to assemble stepwise ...
Jingdong Cheng, J. Baßler, Paulina Fischer, B. Lau, N. Kellner, Ruth Kunze, S. Griesel, Martina Kallas, O. Berninghausen, Daniela Strauss, R. Beckmann, E. Hurt   +11 more
semanticscholar   +3 more sources

Yeast Kre33 and human NAT10 are conserved 18S rRNA cytosine acetyltransferases that modify tRNAs assisted by the adaptor Tan1/THUMPD1

Nucleic Acids Research, 2015
The function of RNA is subtly modulated by post-transcriptional modifications. Here, we report an important crosstalk in the covalent modification of two classes of RNAs. We demonstrate that yeast Kre33 and human NAT10 are RNA cytosine acetyltransferases
Sunny Sharma, Jean-Louis Langhendries, Peter Watzinger, P. Kötter, K. Entian, D. Lafontaine   +5 more
semanticscholar   +3 more sources

H/ACA snR30 snoRNP guides independent 18S rRNA subdomain formation. [PDF]

Nat Commun
Abstract Ribosome biogenesis follows a cascade of pre-rRNA folding and processing steps, coordinated with ribosomal protein incorporation. Nucleolar 90S pre-ribosomes are well-described stable intermediates, composed of pre-18S rRNA, ribosomal S-proteins, U3 snoRNA, and ~70 assembly factors.
Fischer P, Thoms M, Lau B, Denk T, Kuvshinova M, Berninghausen O, Flemming D, Hurt E, Beckmann R.   +8 more
europepmc   +4 more sources

18S rRNA gene metabarcoding for investigation of gastrointestinal parasite diversity in great cormorants [PDF]

Scientific Reports
The great cormorant (Phalacrocorax carbo) is a migratory, fish-eating bird that may act as a carrier for various pathogens, raising potential ecological and public health concerns.
Subin Lee, Badriah Alkathiri, Chang Hyeon Lee, Heon Woo Lee, Dong-Hyuk Jeong, Ju Yeong Kim, Seongjun Choe, Seung-Hun Lee   +7 more
doaj   +2 more sources

Evaluation of coccidia DNA in irrigation pond water and wastewater sludge associated with Cyclospora cayetanensis 18S rRNA gene qPCR detections [PDF]

Microbiology Spectrum
The coccidian parasite Cyclospora cayetanensis is the causative agent for foodborne outbreaks of cyclosporiasis disease and multiple annual fresh produce recalls.
Jessica Hofstetter, Ann Arfken, Amy Kahler, Yvonne Qvarnstrom, Camila Rodrigues, Mia Mattioli   +5 more
doaj   +2 more sources

Development of a Multiplex PCR for Simultaneous Detection of Blueberry Red Ringspot Virus and Blueberry Scorch Virus Including an Internal Control [PDF]

Research in Plant Disease, 2023
Blueberry red ringspot virus (BRRSV) and blueberry scorch virus (BlScV) are included in the quarantine virus list managed by the Korean Animal and Plant Quarantine Agency.
Hae Min Lee, Eun Gyeong Song, Ki Hyun Ryu   +2 more
doaj   +1 more source