Results 31 to 40 of about 248,926 (292)

Vitamin D Status of HIV-Infected Women and its Association with HIV Disease Progression, Anemia, and Mortality. [PDF]

, 2010
Vitamin D has a potential role in slowing HIV disease progression and preventing mortality based on its extensive involvement in the immune system; however, this relationship has not been examined in large studies or in resource-limited settings. Vitamin
Adrian V. Hernandez, David Hunter, Donna Spiegelman, Edward Giovannucci, Ellen Hertzmark, Ferdinand M. Mugusi, Gernard I. Msamanga, Said Aboud, Saurabh Mehta, Wafaie W. Fawzi   +9 more
core   +10 more sources

Cyclooxygenase-2 mediates microglial activation and secondary dopaminergic cell death in the mouse MPTP model of Parkinson's disease

Journal of Neuroinflammation, 2006
Background Accumulating evidence suggests that inflammation plays an important role in the progression of Parkinson's disease (PD). Among many inflammatory factors found in the PD brain, cyclooxygenase (COX), specifically the inducible isoform, COX-2, is
Hunter Randy L, Nguyen Xuan V, Choi Dong-Young, Liu Mei, Vijitruth Rattanavijit, Bing Guoying   +5 more
doaj   +1 more source

Testosterone deficiency increases hospital readmission and mortality rates in male patients with heart failure. [PDF]

, 2015
BackgroundTestosterone deficiency in patients with heart failure (HF) is associated with decreased exercise capacity and mortality; however, its impact on hospital readmission rate is uncertain.
Alves, Maria-Janieire de Nazaré Nunes, Arap, Marco Antônio, Barretto, Antônio Carlos Pereira, Fonseca, Guilherme, Groehs, Raphaela Vilar Ramalho, Middlekauff, Holly R, Negrão, Carlos Eduardo, Santos, Marcelo Rodrigues dos, Sayegh, Ana Luiza Carrari, Trombetta, Ivani Credidio   +9 more
core   +3 more sources

Late-onset thymidine kinase 2 deficiency: a review of 18 cases [PDF]

, 2019
BACKGROUND: TK2 gene encodes for mitochondrial thymidine kinase, which phosphorylates the pyrimidine nucleosides thymidine and deoxycytidine. Recessive mutations in the TK2 gene are responsible for the 'myopathic form' of the mitochondrial depletion ...
Caballero Eraso, Candelaria, Domínguez González, Cristina, Fernández Torrón, Roberto, Fuiza Luces, Carmen, García García, Jorge M., Hernández Laín, Aurelio, Hernández Voth, Ana R., Paradas, Carmen, Rivas, Eloy, Sayas Catalán, Javier   +9 more
core   +1 more source

Knockdown of APOPT1/COA8 Causes Cytochrome c Oxidase Deficiency, Neuromuscular Impairment, and Reduced Resistance to Oxidative Stress in Drosophila melanogaster

Frontiers in Physiology, 2019
Cytochrome c oxidase (COX) deficiency is the biochemical hallmark of several mitochondrial disorders, including subjects affected by mutations in apoptogenic-1 (APOPT1), recently renamed as COA8 (HGNC:20492).
Michele Brischigliaro, Samantha Corrà, Claudia Tregnago, Erika Fernandez-Vizarra, Massimo Zeviani, Massimo Zeviani, Rodolfo Costa, Cristiano De Pittà   +7 more
doaj   +1 more source

Circulating 250HD, dietary vitamin D, PTH, and calcium associations with incident cardiovascular disease and mortality: The MIDSPAN Family Study [PDF]

, 2012
<p>Context: Observational studies relating circulating 25-hydroxyvitamin D (25OHD) and dietary vitamin D intake to cardiovascular disease (CVD) have reported conflicting results.</p> <p>Objective: Our objective was to investigate the ...
Abu-Rmeileh, Alex McConnachie, Anagnostis, Antonia Hardcastle, Bjelakovic, Bolland, Carole Hart, Carstairs, de Borst, Devereux, Dobnig, Emma Boulton, Food Standards Agency, Forrest, Geraldine McNeil, Giovannucci, Graham Watt, Grandi, Great Britain Committee on Medical Aspects of Food Policy Working Group on the Nutritional Status of the Population of Great Britain Department of Health, Hart, Helen Macdonald, Information Services Division, Jassal, Jia, Knox, Knox, Logue, Macdonald, Mark Upton, Marniemi, Melamed, Michaëlsson, Michos, Naveed Sattar, Orla Doolin, Paul Welsh, Reis, Rhein, Ross, Sattar, Sattar, Scottish Intercollegiate Guidelines Network, Semba, Talwar, Todd, Upton, Wang Wang, Williams, Yarnell, Zittermann   +49 more
core   +1 more source

Copper and bezafibrate cooperate to rescue cytochrome c oxidase deficiency in cells of patients with sco2 mutations

Orphanet Journal of Rare Diseases, 2012
Background Mutations in SCO2 cause cytochrome c oxidase deficiency (COX) and a fatal infantile cardioencephalomyopathy. SCO2 encodes a protein involved in COX copper metabolism; supplementation with copper salts rescues the defect in patients’ cells ...
Casarin Alberto, Giorgi Gianpietro, Pertegato Vanessa, Siviero Roberta, Cerqua Cristina, Doimo Mara, Basso Giuseppe, Sacconi Sabrina, Cassina Matteo, Rizzuto Rosario, Brosel Sonja, M Davidson Mercy, DiMauro Salvatore, Schon Eric A, Clementi Maurizio, Trevisson Eva, Salviati Leonardo   +16 more
doaj   +1 more source

Strategies for Understanding and Reducing the Plasmodium vivax and Plasmodium ovale Hypnozoite Reservoir in Papua New Guinean Children: A Randomised Placebo-Controlled Trial and Mathematical Model [PDF]

, 2015
The undetectable hypnozoite reservoir for relapsing Plasmodium vivax and P. ovale malarias presents a major challenge for malaria control and elimination in endemic countries.
Bassat, Quique, Betuela, Inoni, Brewster, Jessica, Felger, Ingrid, Hofmann, Natalie E., Karl, Stephan, Kinboro, Benson, Kiniboro, Benson, Li Wai Suen, Connie S. N., Lorry, Lina, Mueller, Ivo, Robinson, Leanne J., Samol, Lornah, Schofield, Louis, Siba, Peter M., Silkey, Mariabeth, Tarongka, Nandao, Waltmann, Andreea, Wampfler, Rahel, White, Michael T.   +19 more
core   +7 more sources

Promotion of the inflammatory response in mid colon of complement component 3 knockout mice

Scientific Reports, 2022
To determine whether complement component 3 (C3) deficiency affects its receptor downstream-mediated inflammatory response, the current study was undertaken to measure alterations in the inducible nitric oxide synthase (iNOS)‑mediated cyclooxygenase‑2 ...
Yun Ju Choi, Ji Eun Kim, Su Jin Lee, Jeong Eun Gong, You Jeong Jin, Ho Lee, Dae Youn Hwang   +6 more
doaj   +1 more source

Temporary nutrient deficiency - a difficult case for diagnosis and prognosis by plant analysis [PDF]

, 2000
Plant analysis aims to either detect deficiency at the time of sampling (diagnosis) or predict its occurrence at a later stage of growth (prognosis). Its use is based on the presumption that the plant nutrient status will either be constant with plant ...
Bell, R.W.
core   +2 more sources