Results 81 to 90 of about 487,906 (252)

Regularization for Cox’s proportional hazards model with NP-dimensionality

The Annals of Statistics, 2011
Published in at http://dx.doi.org/10.1214/11-AOS911 the Annals of Statistics (http://www.imstat.org/aos/) by the Institute of Mathematical Statistics (http://www.imstat.org)
Bradic, Jelena, Fan, Jianqing, Jiang, Jiancheng   +2 more
openaire   +4 more sources

Generalized log-logistic proportional hazard model with applications in survival analysis

Journal of Statistical Distributions and Applications, 2016
Proportional hazard (PH) models can be formulated with or without assuming a probability distribution for survival times. The former assumption leads to parametric models, whereas the latter leads to the semi-parametric Cox model which is by far the most
Shahedul A. Khan, Saima K. Khosa
semanticscholar   +1 more source

COX PROPORTIONAL HAZARD AND EXPONENTIAL SURVIVAL ANALYSIS IN PATIENTS WITH END-STAGE CHRONIC KIDNEY FAILURE AT BOJONEGORO

Barekeng
End-stage chronic renal failure is a condition that requires long-term treatment such as haemodialysis and poses a serious threat to patient survival.
Nur Silviyah Rahmi, Achmad Rifai, M. Irfan Islami, Annisa Andra Azifa   +3 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Bootstrap distribution for testing a change in the cox proportional hazard model. [PDF]

, 2000
Lam Yuk Fai.Thesis (M.Phil.)--Chinese University of Hong Kong, 2000.Includes bibliographical references (leaves 41-43).Abstracts in English and Chinese.Chapter 1 --- Basic Concepts --- p.9Chapter 1.1 --- Survival data --- p.9Chapter 1.1.1 --- An ...

core  

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Estimating Time-Varying Effects of Prognostic Factors for Stomach Cancer Patients within a Dynamic Grouped Cox Model [PDF]

, 1996
We describe the identification of prognostic factors in the framework of a completely resected stomach cancer survival-study. For the analysis the dynamic grouped Cox-Model was used allowing for time-varying covariate effects.
Nekarda, H., Stark, M., Wagenpfeil, Stefan   +2 more
core   +1 more source

An Assessment of the Cox Proportional Hazards Regression Model for Epidemiologic Studies

Risk Analysis, 2018
The basic assumptions of the Cox proportional hazards regression model are rarely questioned. This study addresses whether hazard ratio, i.e., relative risk (RR), estimates using the Cox model are biased when these assumptions are violated.
S. Moolgavkar, E. T. Chang, Heather Watson, E. Lau   +3 more
semanticscholar   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source