Results 71 to 80 of about 304,906 (294)

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Analysis of time-to-event for observational studies: Guidance to the use of intensity models

, 2020
This paper provides guidance for researchers with some mathematical background on the conduct of time-to-event analysis in observational studies based on intensity (hazard) models.
Abrahamowicz, Michal, Andersen, Per Kragh, Cook, Richard J, Joly, Pierre, Martinussen, Torben, Perme, Maja Pohar, Taylor, Jeremy MG, Therneau, Terry M, van Houwelingen, Hans C   +8 more
core   +1 more source

A Flexible Link Function for Discrete-Time Duration Models [PDF]

, 2014
This paper proposes a discrete-time hazard regression approach based on the relation between hazard rate models and excess over threshold models, which are frequently encountered in extreme value modelling.
Gertheiss, Jan, Hess, Wolfgang, Tutz, Gerhard   +2 more
core   +1 more source

Prognostic Impact of European LeukemiaNet Genetic Risk Stratification System in Adult Patients With Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
This study aimed to evaluate the prognostic value of ELN2017 in predicting survival outcomes and to assess the impact of clinical and molecular factors such as age, FLT3 and NPM1 mutations, and allogeneic hematopoietic stem cell transplantation (allo‐HSCT).
Mobina Shrestha, Bishwas Mandal, Vishal Mandal, Asis Shrestha, Amir Babu Shrestha   +4 more
wiley   +1 more source

Analisis Faktor Yang Memengaruhi Laju Kesembuhan Pasien Tuberkulosis Paru Di RSUD Dr. Soetomo Tahun 2015 Menggunakan Regresi Weibull Dan Regresi Cox Proportional Hazard [PDF]

, 2016
Tuberkulosis (TB) merupakan salah satu penyakit menular yang dapat menyebabkan kematian apabila tidak segera diobati dengan tuntas. Tuberkulosis ini dapat menyerang berbagai organ, terutama paru-paru dikarenakan penularan yang paling mudah melalui udara.
Monica, Y. S. (Yurike), Purhadi, P. (Purhadi)   +1 more
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Modeling and Predicting the Popularity of Online Contents with Cox Proportional Hazard Regression Model [PDF]

, 2012
Special Issue on Advances in Web IntelligenceInternational audienceWe propose a general framework which can be used for modeling and predicting the popularity of online contents.
Lee, Jong Gun, Moon, Sue, Salamatian, Kavé   +2 more
core   +3 more sources

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

What Determines the Duration of Stay of Immigrants in Germany?: Evidence from a Longitudinal Duration Analysis [PDF]

We analyze the return-migration of German immigrants using the latest data of the German Socio- Economic Panel from 1984 to 2006. We conduct a Cox proportional hazard model with years of residence in Germany as waiting time.
Heiko Peters, Sebastian Gundel
core  

Bootstrap distribution for testing a change in the cox proportional hazard model. [PDF]

, 2000
Lam Yuk Fai.Thesis (M.Phil.)--Chinese University of Hong Kong, 2000.Includes bibliographical references (leaves 41-43).Abstracts in English and Chinese.Chapter 1 --- Basic Concepts --- p.9Chapter 1.1 --- Survival data --- p.9Chapter 1.1.1 --- An ...

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