Results 51 to 60 of about 304,906 (294)

Estimation of the Base Hazard Function by Bootstrapping [PDF]

, 2004
This thesis examines the techniques in estimating the base hazard function by bootstrapping. The base hazard function is a crucial part of survival analysis. It is used to construct an estimate of the proportional hazard model for every individual. As
Arlin, Rifina
core  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Employee’s attrition prediction using survival analysis and cox proportional hazard model

JITCE (Journal of Information Technology and Computer Engineering), 2019
In any industry attrition is a big problem, whether it is about employee attrition of an organization or customer attrition of an e-commerce site. If we can accurately predict that which customer or employee can leave their current company/organization ...
Krishna Kumar Mohbey
doaj  

ANALISIS SURVIVAL PADA DATA ASURANSI KESEHATAN DENGAN PENGAPLIKASIAN MODEL COX PROPORTIONAL HAZARD [PDF]

, 2015
Asuransi kesehatan adalah asuransi yang memberikan santunan berupa sejumlah uang untuk biaya pengobatan dan perawatan di bidang kesehatan sebagai sarana pengalihan kemungkinan risiko atau kerugian dari tertanggung kepada penanggung.
Rahma Nurfajrini
core  

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Analysis of time to event outcomes in randomized controlled trials by generalized additive models. [PDF]

PLoS ONE, 2015
BACKGROUND:Randomized Controlled Trials almost invariably utilize the hazard ratio calculated with a Cox proportional hazard model as a treatment efficacy measure.
Christos Argyropoulos, Mark L Unruh
doaj   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Application of Artificial Neural Network in Predicting the Survival Rate of Gastric Cancer Patients [PDF]

Iranian Journal of Public Health, 2011
"nBackground: The aim of this study was to predict the survival rate of Iranian gastric cancer patients using the Cox proportional hazard and artificial neural network models as well as comparing the ability of these approaches in predicting the ...
A Biglarian, E Hajizadeh, A Kazemnejad, MR Zali   +3 more
doaj   +2 more sources

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Time to recovery from visceral leishmaniasis and its predictors of mature visceral leishmaniasis patients admitted at Metema Hospital, Metema, Ethiopia

Scientific Reports
Visceral leishmaniasis (VL) is a neglected tropical disease that mostly affects the working-class and impoverished segments of society, having a significant negative effect on the economic development of the affected nation.
Habitamu Wudu, Chekol Alemu
doaj   +1 more source