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Comparison of Cox proportional hazards regression and generalized Cox regression models applied in dementia risk prediction

open access: yesAlzheimer’s & Dementia: Translational Research & Clinical Interventions, 2020
Introduction The frequently used Cox regression applies two critical assumptions, which might not hold for all predictors. In this study, the results from a Cox regression model (CM) and a generalized Cox regression model (GCM) are compared. Methods Data
Jantje Goerdten   +2 more
doaj   +2 more sources

Partial-linear single-index Cox regression models with multiple time-dependent covariates [PDF]

open access: yesBMC Medical Research Methodology
Background In cohort studies with time-to-event outcomes, covariates of interest often have values that change over time. The classical Cox regression model can handle time-dependent covariates but assumes linear effects on the log hazard function, which
Myeonggyun Lee   +8 more
doaj   +2 more sources

Cox Point Process Regression [PDF]

open access: yesIEEE Transactions on Information Theory, 2022
Point processes in time have a wide range of applications that include the claims arrival process in insurance or the analysis of queues in operations research. Due to advances in technology, such samples of point processes are increasingly encountered. A key object of interest is the local intensity function.
Álvaro Gajardo, Hans-Georg Müller
openaire   +2 more sources

Cox regression with linked data [PDF]

open access: yesStatistics in Medicine, 2023
Record linkage is increasingly used, especially in medical studies, to combine data from different databases that refer to the same entities. The linked data can bring analysts novel and valuable knowledge that is impossible to obtain from a single database.
Vo, Thanh Huan   +6 more
openaire   +6 more sources

Features of using Cox regression in various instrumental environments

open access: yesВестник университета, 2022
The presence of large amounts of data in information and analytical systems makes it necessary to study them using machine learning and artificial intelligence methods.
I. V. Kramarenko, L. A. Konstantinova
doaj   +1 more source

Assumption-Lean Cox Regression

open access: yesJournal of the American Statistical Association, 2022
Inference for the conditional association between an exposure and a time-to-event endpoint, given covariates, is routinely based on partial likelihood estimators for hazard ratios indexing Cox proportional hazards models. This approach is flexible and makes testing straightforward, but is nonetheless not entirely satisfactory.
Stijn Vansteelandt   +3 more
openaire   +3 more sources

Sinusoidal Cox Regression—A Rare Cancer Example

open access: yesCancer Informatics, 2010
Evidence of an association between survival time and date of birth would suggest an etiologic role for a seasonally variable environmental exposure occurring within a narrow perinatal time period.
Jimmy Thomas Efird
doaj   +2 more sources

Gene signature for prognosis in comparison of pancreatic cancer patients with diabetes and non-diabetes [PDF]

open access: yesPeerJ, 2020
Background Pancreatic cancer (PC) has much weaker prognosis, which can be divided into diabetes and non-diabetes. PC patients with diabetes mellitus will have more opportunities for physical examination due to diabetes, while pancreatic cancer patients ...
Mingjun Yang   +5 more
doaj   +2 more sources

An exponential bound for Cox regression [PDF]

open access: yesStatistics & Probability Letters, 2012
We present an asymptotic exponential bound for the deviation of the survival function estimator of the Cox model. We show that the bound holds even when the proportional hazards assumption does not hold.
Goldberg, Y., Kosorok, M. R.
openaire   +3 more sources

Image Based Data Mining Using Per-voxel Cox Regression

open access: yesFrontiers in Oncology, 2020
Image Based Data Mining (IBDM) is a novel analysis technique allowing the interrogation of large amounts of routine radiotherapy data. Using this technique, unexpected correlations have been identified between dose close to the prostate and biochemical ...
Andrew Green   +11 more
doaj   +1 more source

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