Results 41 to 50 of about 414,926 (263)
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Neurotoxicity is a rare, often dose‐limiting adverse effect of methotrexate (MTX) therapy that disproportionally affects Latino children. Factors contributing to the observed disparity are not well understood. This study leveraged admixture mapping to identify genetic regions associated with MTX‐related neurotoxicity susceptibility ...
Rachel D. Harris +24 more
wiley +1 more source
Jurnal Economia, 2020 : This study aims to analyze the difference in job search duration and business preparation duration based on education level, training, job experience, marital status, age, and sex.
Hendri Cahyo Dwi Safitri +1 more
doaj +1 more source
Impact of Metastatic Patterns on Survival and Response to Therapy in Neuroblastoma
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background While the presence of metastases in neuroblastoma (NB) is a well‐established prognostic factor, the clinical significance of dissemination patterns and tumour burden and their impact on response and survival remains poorly understood.
Mariona Morell‐Daniel +15 more
wiley +1 more source
Cox Regression in Survival Analysis: Practical Insights for Clinicians
Acta Médica PortuguesaSurvival analysis is a fundamental tool in clinical research for evaluating time-to-event outcomes. While the Kaplan-Meier method remains a widely used univariable approach for estimating survival probabilities and comparing groups, it does not account ...
António Gomes +3 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Introduction Nephrogenic rests (NRs) and nephroblastomatosis (NBM) are precursor lesions for development of Wilms tumor (WT). Their association with the risk of relapse has not been properly assessed, partly due to misunderstanding of their diagnostic criteria and terminology.
Gordan M. Vujanić +5 more
wiley +1 more source
High-Dimensional Cox Regression Analysis in Genetic Studies with Censored Survival Outcomes
Journal of Probability and Statistics, 2012 With the advancement of high-throughput technologies, nowadays high-dimensional genomic and proteomic data are easy to obtain and have become ever increasingly important in unveiling the complex etiology of many diseases. While relating a large number of
Jinfeng Xu
doaj +1 more source
BMC Bioinformatics, 2022 Background Breast cancer is one of the most common cancers in women. It is necessary to classify breast cancer subtypes because different subtypes need specific treatment.
Juntao Li, Hongmei Zhang, Fugen Gao
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT We report a retrospective single‐center analysis of pediatric patients with relapsed or refractory B‐cell precursor acute lymphoblastic leukemia focusing on relapses outside of the typical locations, bone marrow, central nervous system, or testes.
Johanna Kunz +7 more
wiley +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Barekeng, 2021 This research purpose is to analyze the relationship between food intake factors (fruit, soy, milk, caffeine, red meat, garlic, ginger, seafood, cheese, green tea, brown rice, wheat, potatoes, bean sprouts, mustard greens, soft drinks and alcohol) on ...
Ning Eliyati +3 more
doaj +1 more source