A comparison of time dependent Cox regression, pooled logistic regression and cross sectional pooling with simulations and an application to the Framingham Heart Study [PDF]
Background Typical survival studies follow individuals to an event and measure explanatory variables for that event, sometimes repeatedly over the course of follow up.
Julius S. Ngwa +6 more
doaj +10 more sources
U-shaped link of health checkup data and need for care using a time-dependent cox regression model with a restricted cubic spline [PDF]
We explored risk indicators likely to result in older adults needing certified long-term care in Japan and ascertained whether this relationship forms a U-shaped link. We analyzed a community-based cohort of residents in Kitanagoya City, Aichi Prefecture,
Masahiro Nakatochi +4 more
doaj +6 more sources
Association of C-reactive protein and non-steroidal anti-inflammatory drugs with cardiovascular events in patients with psoriatic arthritis: a time-dependent Cox regression analysis [PDF]
Aims: Psoriatic arthritis (PsA) is associated with accelerated atherosclerosis due to underlying inflammation. Whether inflammatory burden and drugs used to suppress inflammation over time are associated with cardiovascular (CV) events remained unclear ...
Steven H. Lam +7 more
doaj +6 more sources
Impact of nucleos(t)ide analogues on the risk of hepatocellular carcinoma in chronic hepatitis B patients: a time-dependent Cox regression analysis [PDF]
Background and aimsThe preventive effect of nucleos(t)ide analog (NA) use on HCC development in patients with chronic hepatitis B (CHB) is controversial due to the difficulty of conducting randomized controlled trials.Approach and resultsIn this single ...
Makoto Moriyama +12 more
doaj +7 more sources
Dynamic biomarkers and Cox regression with time-dependent covariate for mortality prediction in severe fever with thrombocytopenia syndrome [PDF]
Severe fever with thrombocytopenia syndrome (SFTS) is a fatal tick-borne infectious disease that lacks effective treatments. Dynamic analysis that reflects changes in the SFTS patient’s condition is needed. This study aimed to evaluate the time-dependent
Hyun Ji Woo +20 more
doaj +6 more sources
Partial-linear single-index Cox regression models with multiple time-dependent covariates [PDF]
Background In cohort studies with time-to-event outcomes, covariates of interest often have values that change over time. The classical Cox regression model can handle time-dependent covariates but assumes linear effects on the log hazard function, which
Myeonggyun Lee +8 more
doaj +4 more sources
Post-tuberculosis mortality risk among immigrants to British Columbia, Canada, 1985-2015: a time-dependent Cox regression analysis of linked immigration, public health, and vital statistics data. [PDF]
Basham CA +4 more
europepmc +3 more sources
Machine learning prediction of tuberculosis mortality: a comparative analysis of random survival forest and cox regression models [PDF]
Background Survival analysis is widely used to predict time-to-event outcomes, with the Cox regression model being a standard approach. However, machine learning methods such as Random Survival Forests (RSF) can capture complex, non-linear relationships ...
Azeez Adeboye +3 more
doaj +2 more sources
Machine learning-based prognostic model for local control prediction in lung cancer patients undergoing stereotactic body radiation therapy: a preliminary study [PDF]
Purpose Predicting local recurrence after stereotactic body radiation therapy (SBRT) for lung cancer remains challenging. This study aims to develop a machine learning (ML)-based prognostic model for local control (LC) prediction by comparing different ...
Bao-Tian Huang +3 more
doaj +2 more sources
A prognostic nomogram for colorectal cancer based on ubiquitin-specific protease 21 expression: a retrospective cohort study [PDF]
BackgroundColorectal cancer (CRC) remains a leading cause of cancer-related mortality worldwide, and substantial prognostic heterogeneity exists among patients with similar TNM stages.
Hua Chen +4 more
doaj +2 more sources

