Estimation in a Cox Proportional Hazards Cure Model [PDF]
Summary.Some failure time data come from a population that consists of some subjects who are susceptible to and others who are nonsusceptible to the event of interest. The data typically have heavy censoring at the end of the follow‐up period, and a standard survival analysis would not always be appropriate.
Sy, Judy P., Taylor, Jeremy M. G.
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Gradient lasso for Cox proportional hazards model [PDF]
AbstractMotivation: There has been an increasing interest in expressing a survival phenotype (e.g. time to cancer recurrence or death) or its distribution in terms of a subset of the expression data of a subset of genes. Due to high dimensionality of gene expression data, however, there is a serious problem of collinearity in fitting a prediction model,
Insuk Sohn +3 more
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Tree-augmented Cox proportional hazards models [PDF]
We study a hybrid model that combines Cox proportional hazards regression with tree-structured modeling. The main idea is to use step functions, provided by a tree structure, to 'augment' Cox (1972) proportional hazards models. The proposed model not only provides a natural assessment of the adequacy of the Cox proportional hazards model but also ...
Su, Xiaogang, Tsai, Chih Ling
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Generating Survival Times to Simulate Cox Proportional Hazards Models [PDF]
This paper discusses techniques to generate survival times for simulation studies regarding Cox proportional hazards models. In linear regression models, the response variable is directly connected with the considered covariates, the regression ...
Augustin, Thomas +2 more
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Numerous methods and approaches have been developed for generating time-to-event data from the Cox Proportional Hazards (CPH) model; however, they often require specification of a parametric distribution for the baseline hazard even though the CPH model ...
Jennifer L. Delzeit, Devin C. Koestler
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A mixed model approach for structured hazard regression [PDF]
The classical Cox proportional hazards model is a benchmark approach to analyze continuous survival times in the presence of covariate information. In a number of applications, there is a need to relax one or more of its inherent assumptions, such as ...
Fahrmeir, Ludwig, Kneib, Thomas
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An exact corrected log-likelihood function for Cox's proportional hazards model under measurement error and some extensions [PDF]
This paper studies Cox`s proportional hazards model under covariate measurement error. Nakamura`s (1990) methodology of corrected log-likelihood will be applied to the so called Breslow likelihood, which is, in the absence of measurement error ...
Augustin, Thomas
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A penalized Cox proportional hazards model with multiple time-varying exposures [PDF]
In recent pharmacoepidemiology research, the increasing use of electronic medication dispensing data provides an unprecedented opportunity to examine various health outcomes associated with long-term medication usage.
Gao, Sujuan, Liu, Hai, Wang, Chenkun
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Cox regression survival analysis with compositional covariates: application to modelling mortality risk from 24-h physical activity patterns [PDF]
Survival analysis is commonly conducted in medical and public health research to assess the association of an exposure or intervention with a hard end outcome such as mortality. The Cox (proportional hazards) regression model is probably the most popular
Chastin, S.F.M. +4 more
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Comparison of radiomic feature aggregation methods for patients with multiple tumors
Radiomic feature analysis has been shown to be effective at analyzing diagnostic images to model cancer outcomes. It has not yet been established how to best combine radiomic features in cancer patients with multifocal tumors.
Enoch Chang +7 more
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