Results 21 to 30 of about 281,063 (279)

Estimation in a Cox Proportional Hazards Cure Model [PDF]

open access: yesBiometrics, 2000
Summary.Some failure time data come from a population that consists of some subjects who are susceptible to and others who are nonsusceptible to the event of interest. The data typically have heavy censoring at the end of the follow‐up period, and a standard survival analysis would not always be appropriate.
Sy, Judy P., Taylor, Jeremy M. G.
openaire   +4 more sources

Gradient lasso for Cox proportional hazards model [PDF]

open access: yesBioinformatics, 2009
AbstractMotivation: There has been an increasing interest in expressing a survival phenotype (e.g. time to cancer recurrence or death) or its distribution in terms of a subset of the expression data of a subset of genes. Due to high dimensionality of gene expression data, however, there is a serious problem of collinearity in fitting a prediction model,
Insuk Sohn   +3 more
openaire   +2 more sources

Tree-augmented Cox proportional hazards models [PDF]

open access: yesBiostatistics, 2005
We study a hybrid model that combines Cox proportional hazards regression with tree-structured modeling. The main idea is to use step functions, provided by a tree structure, to 'augment' Cox (1972) proportional hazards models. The proposed model not only provides a natural assessment of the adequacy of the Cox proportional hazards model but also ...
Su, Xiaogang, Tsai, Chih Ling
openaire   +4 more sources

Generating Survival Times to Simulate Cox Proportional Hazards Models [PDF]

open access: yes, 2003
This paper discusses techniques to generate survival times for simulation studies regarding Cox proportional hazards models. In linear regression models, the response variable is directly connected with the considered covariates, the regression ...
Augustin, Thomas   +2 more
core   +2 more sources

Simulating time-to-event data under the Cox proportional hazards model: assessing the performance of the non-parametric Flexible Hazards Method

open access: yesFrontiers in Applied Mathematics and Statistics, 2023
Numerous methods and approaches have been developed for generating time-to-event data from the Cox Proportional Hazards (CPH) model; however, they often require specification of a parametric distribution for the baseline hazard even though the CPH model ...
Jennifer L. Delzeit, Devin C. Koestler
doaj   +1 more source

A mixed model approach for structured hazard regression [PDF]

open access: yes, 2004
The classical Cox proportional hazards model is a benchmark approach to analyze continuous survival times in the presence of covariate information. In a number of applications, there is a need to relax one or more of its inherent assumptions, such as ...
Fahrmeir, Ludwig, Kneib, Thomas
core   +4 more sources

An exact corrected log-likelihood function for Cox's proportional hazards model under measurement error and some extensions [PDF]

open access: yes, 2002
This paper studies Cox`s proportional hazards model under covariate measurement error. Nakamura`s (1990) methodology of corrected log-likelihood will be applied to the so called Breslow likelihood, which is, in the absence of measurement error ...
Augustin, Thomas
core   +1 more source

A penalized Cox proportional hazards model with multiple time-varying exposures [PDF]

open access: yes, 2017
In recent pharmacoepidemiology research, the increasing use of electronic medication dispensing data provides an unprecedented opportunity to examine various health outcomes associated with long-term medication usage.
Gao, Sujuan, Liu, Hai, Wang, Chenkun
core   +1 more source

Cox regression survival analysis with compositional covariates: application to modelling mortality risk from 24-h physical activity patterns [PDF]

open access: yes, 2020
Survival analysis is commonly conducted in medical and public health research to assess the association of an exposure or intervention with a hard end outcome such as mortality. The Cox (proportional hazards) regression model is probably the most popular
Chastin, S.F.M.   +4 more
core   +1 more source

Comparison of radiomic feature aggregation methods for patients with multiple tumors

open access: yesScientific Reports, 2021
Radiomic feature analysis has been shown to be effective at analyzing diagnostic images to model cancer outcomes. It has not yet been established how to best combine radiomic features in cancer patients with multifocal tumors.
Enoch Chang   +7 more
doaj   +1 more source

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