Results 41 to 50 of about 14,803,607 (247)

Prognostic Factors in Patients With Colorectal Cancer at Hospital Universiti Sains Malaysia

open access: yesAsian Journal of Surgery, 2010
To determine the 5-year survival rate and prognostic factors for survival in patients with colorectal cancer treated at the Surgical Unit, Hospital Universiti Sains Malaysia (HUSM), Kelantan, Malaysia.
Anis Kausar Ghazali   +3 more
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Cox proportional hazards regression model.

open access: yes, 2014
Cox proportional hazards regression model (n = 309 episodes in 1117 patients).Cox proportional hazards regression model.
Juan Wang (115708)   +10 more
core   +1 more source

Identification of a competing risks model with unknown transformations of latent failure times [PDF]

open access: yes, 2005
This paper is concerned with identification of a competing risks model with unknown transformations of latent failure times. The model in this paper includes, as special cases, competing risks versions of proportional hazards, mixed proportional ...
Lee, S., Lee, Sokbae, Sokbae (Simon) Lee
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Testing for Proportional Hazards with Unrestricted Univariate Unobserved Heterogeneity [PDF]

open access: yes, 2009
We develop tests of the proportional hazards assumption, with respect to a continuous covariate, in the presence of unobserved heterogeneity with unknown distribution at the individual observation level.
Bhattacharjee, Arnab   +1 more
core  

Estimation of treatment effects in weighted log-rank tests

open access: yesContemporary Clinical Trials Communications, 2017
Non-proportional hazards have been observed in clinical trials. The log-rank test loses power and the standard Cox model generally produces biased estimates under such conditions.
Ray S. Lin, Larry F. León
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Determining the Factors Affecting the Survival of HIV Patients: Comparison of Cox Model and the Random Survival Forest Method [PDF]

open access: yesDisease and Diagnosis, 2019
Background: In recent years, sexually transmitted diseases such as AIDS have become an epidemic and are growing rapidly. Given the importance of controlling the disease in recent years, the awareness of the most important risk factors associated with ...
Nasim Karimi   +5 more
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

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