Results 51 to 60 of about 851,409 (271)
Molecular Oncology, EarlyView.Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla +5 more
wiley +1 more source
Molecular Oncology, EarlyView.This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu +12 more
wiley +1 more source
St. Petersburg Polytechnical University Journal: Physics and Mathematics, 2021 The article suggests an extension and refinement of the existing model for incomplete estimation of the person’s behavior characteristics using several last episodes of his risky behavior and including individual characteristics and other factors, in ...
Stoliarova Valeriia, Tulupyev Alexander
doaj +1 more source
Inference on Counterfactual Distributions [PDF]
, 2012 Counterfactual distributions are important ingredients for policy analysis and decomposition analysis in empirical economics. In this article we develop modeling and inference tools for counterfactual distributions based on regression methods.
Chernozhukov, Victor +2 more
core +6 more sources
Molecular Oncology, EarlyView.This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh +8 more
wiley +1 more source
Prognostic Factors on Survival of Rasoul-e-Akram Hospital Patients with Colorectal Cancer: A Survival Analysis [PDF]
Journal of Clinical and Diagnostic Research, 2019 Introduction: Colorectal Cancer (CRC) also called colon cancer or intestine cancer is characterised by cancerous growth of cells in the rectum, colon and appendix.
Shahram Agah +4 more
doaj +1 more source
Frontiers in Genetics, 2021 Oral squamous cell carcinoma (OSCC) has a high mortality rate (∼50%), and the 5-year overall survival rate is not optimal. Cyto- and histopathological examination of cancer tissues is the main strategy for diagnosis and treatment.
Hui-Ching Wang +14 more
doaj +1 more source
Two Survival Tree Models for Myocardial Infarction Patients [PDF]
, 2000 In the search of a better prognostic survival model for post-acute myocardial infarction patients, the scientists at the Technical University of Munich's "Klinikum rechts der Isar" and the German Heart Center in Munich have developed some new parameters ...
Pashova, Victoria, Ulm, Kurt
core +1 more source
Molecular Oncology, EarlyView.The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song +11 more
wiley +1 more source
Identification of a 3-Gene Model as Prognostic Biomarker in Patients With Gastric Cancer
Frontiers in Oncology, 2022 ObjectiveAlthough the incidence of gastric cancer (GC) is decreasing, GC remains one of the leading cancers in the world. Surgical resection, radiotherapy, chemotherapy, and neoadjuvant therapy have advanced, but patients still face the risk of ...
Siming Xue +14 more
doaj +1 more source