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Encephalitis caused by Coxiella burnetii [PDF]
Annals of Neurology, 1986 AbstractAcute infection with Coxiella burnetii usually results in a self‐limited illness, but it can occasionally cause chronic endocarditis or hepatitis. Headache is a common presenting symptom of acute infection with this agent, but specific neurological abnormalities are rare.
Robert G. Brooks +2 more
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2002
Publisher Summary The aetiological agent of Q fever, Coxiella burnetii (C. burnetii), is a bacterial obligate intracellular parasite that replicates within the phagolysosome of its eukaryotic host. C. burnetii is an obligate intracellular bacterium that displays a prototypic Gram-negative cell wall structure when observed by electron microscopy.
James E. Samuel, Robert A. Heinzen
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Publisher Summary The aetiological agent of Q fever, Coxiella burnetii (C. burnetii), is a bacterial obligate intracellular parasite that replicates within the phagolysosome of its eukaryotic host. C. burnetii is an obligate intracellular bacterium that displays a prototypic Gram-negative cell wall structure when observed by electron microscopy.
James E. Samuel, Robert A. Heinzen
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Annals of the New York Academy of Sciences, 2005
Abstract:Coxiella burnetiiis an obligate intracellular bacterium that causes a worldwide zoonosis, Q fever, and can be misused as a biological warfare agent. Infection in animals (coxiellosis) is mostly persistent. Infection in humans is often asymptomatic, but it can manifest as an acute disease (usually a self‐limited flu‐like illness, pneumonia, or ...
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Abstract:Coxiella burnetiiis an obligate intracellular bacterium that causes a worldwide zoonosis, Q fever, and can be misused as a biological warfare agent. Infection in animals (coxiellosis) is mostly persistent. Infection in humans is often asymptomatic, but it can manifest as an acute disease (usually a self‐limited flu‐like illness, pneumonia, or ...
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COXIELLA BURNETII ENDOCARDITIS IN A CHILD
The Pediatric Infectious Disease Journal, 1997Chronic Q fever is a rare but increasingly recognized cause of culture-negative endocarditis in adults. The clinical manifestations of this infection are not well-known in children. In this paper we report Q fever endocarditis in a child.
Cornelie Jäger +3 more
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New insights in Coxiella burnetii infection: diagnosis and therapeutic update
Expert Review of Anti-Infective Therapy, 2019Introduction: Coxiella burnetii infection is still challenging physicians, mainly because no international coordination has been stated to standardize the therapeutic strategy and improve the clinical outcomes.
C. Melenotte, M. Million, D. Raoult
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The Coxiella burnetii Parasitophorous Vacuole
2012Coxiella burnetii is a bacterial intracellular parasite of eucaryotic cells that replicates within a membrane-bound compartment, or "parasitophorous vacuole" (PV). With the exception of human macrophages/monocytes, the consensus model of PV trafficking in host cells invokes endolysosomal maturation culminating in lysosome fusion. C.
María Isabel Colombo +2 more
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Coxiella burnetii Not a Rickettsia
Microbe Magazine, 2011The recent article describing the outbreak of Q fever in the Netherlands (Microbe, April 2011, p. 159) was both well written and impactful in shedding light on what is very likely an underappreciated cause of febrile illness worldwide, especially where people live in close contact with ruminant livestock. In the article, the causative agent of Q fever,
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Gene Inactivation in Coxiella burnetii
2014Coxiella burnetii, the agent of human Q fever, is a zoonotic bacterial pathogen with a worldwide distribution. Owing to an historic lack of methods for genetic manipulation, virulence factors deployed by this bacterium for disease pathogenesis are poorly understood. However, the recent advance of host cell-free (axenic) growth of C.
Robert A. Heinzen, Paul A. Beare
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Coxiella burnetii Secretion Systems
2012The ability of bacteria to transport proteins across their membranes is integral for interaction with their environment. Distinct families of secretion systems mediate bacterial protein secretion. The human pathogen, Coxiella burnetii encodes components of the Sec-dependent secretion pathway, an export system used for type IV pilus assembly, and a ...
Hayley J. Newton +2 more
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Developmental Biology of Coxiella burnetii
2012The biphasic developmental cycle of Coxiella burnetii is central to the pathogen's natural history and survival. A small, dormant cell morphotype (the small-cell variant or SCV) allows this obligate intracellular bacterium to persist for extended periods outside of host cells, resist environmental conditions that would be lethal to most prokaryotes ...
Rahul Raghavan, Michael F. Minnick
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