Results 111 to 120 of about 40,540 (250)
Scientific Reports, 2016 The IFIH1 gene encodes the pattern recognition receptor MDA5. A common polymorphism in IFIH1 (rs1990760, A946T) confers increased risk for autoimmune disease, including type 1-diabetes (T1D).
Erna Domsgen +8 more
semanticscholar +1 more source
A literature review and case report of hand, foot and mouth disease in an immunocompetent adult [PDF]
, 2017 Background: to report an uncommon case of hand, foot and mouth disease, (HFMD) in an immunocompetent adult; a highly infectious disease, characterized by the appearance of vesicles on the mouth, hands and feet, associated with coxsackieviruses and ...
Jané Salas, Enric +5 more
core +1 more source
Role of Histone Deacetylase and Inhibitors in Cardiovascular Diseases
Cell Proliferation, Volume 58, Issue 12, December 2025.HDACs play an important role in the occurrence and development of cardiovascular diseases, such as myocardial hypertrophy, hypertension, and atherosclerosis. HDAC inhibitors have broad prospects for the treatment of CVD, and different HDAC subtypes can act through different mechanisms.
Li‐Ying Zhang +4 more
wiley +1 more source
Frontiers in Microbiology, 2016 Background: Etiology surveillance of Hand Foot and Mouth disease (HFMD) in Beijing showed that Coxsackievirus A6 (CVA6) became the major pathogen of HFMD in 2013 and 2015.
Jie Li +14 more
semanticscholar +1 more source
A novel mechanism underlying the innate immune response induction upon viral-dependent replication of host cell mRNA: A mistake of +sRNA viruses' replicases [PDF]
, 2017 Viruses are lifeless particles designed for setting virus-host interactome assuring a new generation of virions for dissemination. This interactome generates a pressure on host organisms evolving mechanisms to neutralize viral infection, which places the
Colombo, Maria Isabel +1 more
core +2 more sources
Collapsing Glomerulopathy in Brazil: A Nationwide Descriptive Study
Nephrology, Volume 30, Issue 12, December 2025.This multicenter study describes the characterization and outcomes of a retrospective cohort of collapsing glomerulopathy cases conducted in Brazil. These findings reinforce the understanding of this rare glomerulopathy. ABSTRACT Aim Collapsing glomerulopathy (CG) is a glomerular disease that progresses rapidly to renal replacement therapy (RRT ...
Marcos Adriano Garcia Campos +26 more
wiley +1 more source
Emergence of a Large-Plaque Variant in Mice Infected with Coxsackievirus B3
mBio, 2016 Coxsackieviruses are enteric viruses that frequently infect humans. To examine coxsackievirus pathogenesis, we orally inoculated mice with the coxsackievirus B3 (CVB3) Nancy strain.
Yao Wang, Julie K. Pfeiffer
semanticscholar +1 more source
Synthesis, Antiviral and Antitumor Activity of 2- substituted-5-amidino-benzimidazoles [PDF]
, 2007 We have prepared a set of heterocyclic benzimidazole derivatives bearing amidino substituents at C-5 of benzimidazole ring, by introducing various heterocyclic nuclei (pyridine, N-methyl-pyrrole or imidazole) at C-2, and evaluated their antitumor and ...
Ester, Katja +6 more
core +1 more source
Molecular epidemiology of Coxsackievirus B3
Infection, Genetics and Evolution, 2010 Molecular epidemiological characteristics are needed to understand the impact of Coxsackievirus B3 (CV-B3) infection, since no CV-B3 genotyping literature is available. Twenty-nine CV-B3 Taiwan strains obtained from 1992 to 2005 were analyzed. A phylogenetic tree was constructed based on the 290 nucleotide sequence of the VP1 gene of Taiwan isolates ...
Pei-Yu, Chu +11 more
openaire +2 more sources
A novel microRNA promotes coxsackievirus B4 infection of pancreatic β cells
Frontiers in ImmunologyThe epidemiological association of coxsackievirus B infection with type 1 diabetes suggests that therapeutic strategies that reduce viral load could delay or prevent disease onset.
Salima Lalani +7 more
doaj +1 more source