Results 211 to 220 of about 40,540 (250)

Combating coxsackievirus B infections

Reviews in Medical Virology, 2022
Coxsackieviruses B (CVB) are small, non‐enveloped, single‐stranded RNA viruses belonging to the Enterovirus genus of the Picornaviridae family. They are common worldwide and cause a wide variety of human diseases ranging from those having relatively mild
Abdulaziz Alhazmi, M. Nekoua, Ambroise Mercier, Inès Vergez, F. Sane, E. K. Alidjinou, D. Hober   +6 more
semanticscholar   +5 more sources

Clinical Responses of Oncolytic Coxsackievirus A21 (V937) in Patients With Unresectable Melanoma

Journal of Clinical Oncology, 2021
PURPOSE We evaluated the activity of intratumoral Coxsackievirus A21 (V937) in 57 patients with unresectable stage IIIC or IV melanoma. PATIENTS AND METHODS In this multicenter, open-label, phase II study, patients received up to a total V937 dose of 3 ×
R. Andtbacka, B. Curti, G. Daniels, S. Hallmeyer, E. Whitman, J. Lutzky, L. Spitler, K. Zhou, P. Bommareddy, M. Grose, Meihua Wang, Cai Wu, H. Kaufman   +12 more
semanticscholar   +1 more source

Coxsackievirus-Induced Pancreatitis

Viral Immunology, 2004
In humans, infections with the group B coxsackieviruses (CVBs) range from asymptomatic infections to chronic, debilitating diseases. The CVBs are associated with chronic inflammatory diseases of the pancreas, heart, and central nervous system. A major focus in CVB pathogenesis is to understand the mechanisms by which these viruses cause acute diseases ...
Sally, Huber, Arlene I, Ramsingh
openaire   +2 more sources

Hand, foot, and mouth disease associated with coxsackievirus A10: more serious than it seems

Expert Review of Anti-Infective Therapy, 2019
Introduction: Hand, foot, and mouth disease (HFMD) is a common viral childhood illness, that has been a severe public health concern worldwide, particularly in the Asia-Pacific region. According to epidemiological data of HFMD during the past decade, the
Lian-lian Bian, Fan Gao, Qunying Mao, Shiyang Sun, Xing Wu, Siyuan Liu, Xiaoming Yang, Zhenglun Liang   +7 more
semanticscholar   +1 more source

FATAL COXSACKIEVIRUS A16 INFECTION

The Pediatric Infectious Disease Journal, 2004
A 15-month-old boy presenting with hand, foot and mouth disease died of myocarditis and intractable shock caused by coxsackievirus A16 infection. It is apparent that coxsackievirus A16 infection is not always a benign infection.
Chung-Yi, Wang, Frank, Li Lu, Mei-Hwan, Wu, Chin-Yun, Lee, Li-Min, Huang   +4 more
openaire   +2 more sources

Genome of coxsackievirus B3

Virology, 1987
The entire nucleotide sequence of the coxsackievirus B3 strain Nancy (CB3) genome has been determined from cDNA. The genome is 7396 nucleotides long, and encodes a 2185 amino acid long polyprotein. It exhibits the same gene organization as other enterovirus genomes.
A M, Lindberg, P O, Stålhandske, U, Pettersson   +2 more
openaire   +2 more sources

Coxsackievirus experimental heart diseases

Frontiers in Bioscience, 2003
Many microorganisms, particularly viruses, can cause myocarditis, an inflammatory disease of the heart. The frequency of and major factors that contribute to this disease, including a pronounced gender (male) bias, age and genetic background parameters are discussed, along with signs and symptoms of disease in infants to adults.
Charles, Gauntt, Sally, Huber
openaire   +2 more sources

Genetics of Coxsackievirus Virulence

1997
The first reported isolate of the coxsackieviruses occurred in the upstate New York town of Coxsackie (Dalldorf and Sickles 1948). By the mid-late 1950s (Dalldorf 1955), the coxsackie B viruses (CVBs) had been shown to be agents of severe human inflammatory heart muscle disease (myocarditis) (Montgomery et al. 1955; Gear et al. 1956; Javett et al. 1956;
N M, Chapman, A I, Ramsingh, S, Tracy
openaire   +2 more sources

Combination of soluble coxsackievirus-adenovirus receptor and anti-coxsackievirus siRNAs exerts synergistic antiviral activity against coxsackievirus B3

Antiviral Research, 2009
Coxsackievirus B3 (CVB-3) is a major causative agent of chronic heart muscle infections. The present study describes a cell culture system with an ongoing virus infection to evaluate two novel inhibitory strategies, either individually or combined: (1) RNA interference (RNAi) to degrade cytoplasmatic CVB-3 RNA and (2) a vector-delivered soluble variant
Denise, Werk, Sandra, Pinkert, Albert, Heim, Heinz, Zeichhardt, Hans-Peter, Grunert, Wolfgang, Poller, Volker A, Erdmann, Henry, Fechner, Jens, Kurreck   +8 more
openaire   +2 more sources

Experimental coxsackievirus endocarditis.

JAMA, 1966
Although occasional references to viral endocarditis have appeared in the literature,1,2neither cardiologists nor pathologists generally consider endocarditis or valvulitis to be a complication of viral infection. However, it has been suggested that subendocardial fibroelastosis may be viral in etiology and it has recently been observed that children ...
G E, Burch, N P, DePasquale, S C, Sun, A R, Hale, W J, Mogabgab   +4 more
openaire   +3 more sources