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Clinical Responses of Oncolytic Coxsackievirus A21 (V937) in Patients With Unresectable Melanoma

Journal of Clinical Oncology, 2021
PURPOSE We evaluated the activity of intratumoral Coxsackievirus A21 (V937) in 57 patients with unresectable stage IIIC or IV melanoma. PATIENTS AND METHODS In this multicenter, open-label, phase II study, patients received up to a total V937 dose of 3 ×
R. Andtbacka   +12 more
semanticscholar   +1 more source

Combating coxsackievirus B infections

Reviews in Medical Virology, 2022
Coxsackieviruses B (CVB) are small, non‐enveloped, single‐stranded RNA viruses belonging to the Enterovirus genus of the Picornaviridae family. They are common worldwide and cause a wide variety of human diseases ranging from those having relatively mild
Abdulaziz Alhazmi   +6 more
semanticscholar   +1 more source

Hand, foot, and mouth disease associated with coxsackievirus A10: more serious than it seems

Expert Review of Anti-Infective Therapy, 2019
Introduction: Hand, foot, and mouth disease (HFMD) is a common viral childhood illness, that has been a severe public health concern worldwide, particularly in the Asia-Pacific region. According to epidemiological data of HFMD during the past decade, the
Lian-lian Bian   +7 more
semanticscholar   +1 more source

Immunomodulation by adoptive regulatory T‐cell transfer improves Coxsackievirus B3‐induced myocarditis

The FASEB Journal, 2018
Regulatory T (Treg) cells offer new therapeutic options for controlling undesired systemic and local immune responses. The aim of the current study was to determine the impact of therapeutic Treg administration on systemic and cardiac inflammation and ...
K. Pappritz   +16 more
semanticscholar   +1 more source

Early Treatment of Coxsackievirus B3-Infected Animals With Soluble Coxsackievirus-Adenovirus Receptor Inhibits Development of Chronic Coxsackievirus B3 Cardiomyopathy.

Circulation: Heart Failure, 2019
BACKGROUND Coxsackie-B-viruses (CVB) are frequent causes of acute myocarditis and dilated cardiomyopathy, but an effective antiviral therapy is still not available.
S. Pinkert   +10 more
semanticscholar   +1 more source

Antiviral potential of medicinal plants against HIV, HSV, influenza, hepatitis, and coxsackievirus: A systematic review

Phytotherapy Research, 2018
M. Akram   +9 more
semanticscholar   +1 more source

Development of a reverse transcription recombinase-aided amplification assay for the detection of coxsackievirus A10 and coxsackievirus A6 RNA

Archives of Virology, 2018
Teng-Fei Yan   +7 more
semanticscholar   +1 more source

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