Results 131 to 140 of about 2,546 (158)

Molecular surveillance of coxsackievirus A16 in southern China, 2008–2019

Archives of Virology, 2021
A national surveillance system on hand, foot, and mouth disease (HFMD) was launched in 2008 in China. Since then, millions of HFMD cases have been reported each year, with enterovirus A71 (EV-A71), coxsackievirus A16 (CV-A16), and coxsackievirus A6 (CV-A6) as the major causative pathogens.
Lina Yi, Hanri Zeng, Huanying Zheng, Jinju Peng, Xue Guo, Leng Liu, Qianling Xiong, Limei Sun, Xiaohua Tan, Jianfeng He, Jing Lu, Hui Li   +11 more
openaire   +2 more sources

Recent Advances in Anti-Coxsackievirus A16 Viral Drug Research

Future Medicinal Chemistry, 2022
Hand, foot and mouth disease, a childhood disorder caused by enteroviruses, is intermittently endemic in the Asia-Pacific region and endangers the lives of many infants and young children. Coxsackievirus A16 (CV-A16) is one of the major pathogens causing hand, foot, and mouth disease on occasion, resulting in catastrophic neurological sequelae and ...
Xiaolan Yuan, Ziwei Liu, Li Wan, Wei Liu, Yan Huang, Shuang Cao   +5 more
openaire   +2 more sources

Development of an IgM-capture ELISA for Coxsackievirus A16 infection

Journal of Virological Methods, 2011
Diagnosis of Coxsackievirus A16 (CA16) infection in China relies mainly on reverse transcription-polymerase chain reaction (RT-PCR) that require expensive equipment and special trained personnel, thus making its wide application in health care settings unlikely.
Xu, F. H., He, D. L., He, S. Z., Wu, B., Guan, L., Niu, J. J., Li, L. A., Li, C. A., Weng, Z. X., Yan, Q. A., Yang, L. S., Ge, S. X., Cheng, T., Chen, Y. X., Zhang, J., Xia, N. S.   +15 more
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Hand, Foot, and Mouth Disease (Coxsackievirus A16) in Atlanta

Archives of Pediatrics & Adolescent Medicine, 1967
IN 1958 1 Robinson and his co-workers reported an outbreak of epidemic disease in Toronto characterized by stomatitis, a maculopapular rash, and vesicles on the hands and feet associated with coxsackievirus A16 infection. Since that time, there have been additional reports of similar cases in England, Australia, and the United States. 2-11 This disease
J E, Froeschle, A J, Nahmias, P M, Feorino, G, McCord, Z, Naib   +4 more
openaire   +2 more sources

A murine model of coxsackievirus A16 infection for anti-viral evaluation

Antiviral Research, 2014
Coxsackievirus A16 (CA16) is one of the main causative agents of hand, foot and mouth disease (HFMD), which is a common infectious disease in children. CA16 infection may lead to severe nervous system damage and even death in humans. However, study of the pathogenesis of CA16 infection and development of vaccines and anti-viral agents are hindered ...
Qingwei, Liu, Jinping, Shi, Xulin, Huang, Fei, Liu, Yicun, Cai, Ke, Lan, Zhong, Huang   +6 more
openaire   +2 more sources

Generalized Eruption in a Child With Eczema Due to Coxsackievirus A16

Archives of Dermatology, 1968
A 1-year-old infant with preexisting atopic eczema who developed a generalized vesicular exanthem resembling Kaposi's varicelliform eruption was studied. Virological, serological and cytological studies were compatible with a coxsackievirus A16 infection, while no evidence of infection with herpes simplex, vaccinia, or varicella viruses could be ...
A J, Nahmias, J E, Froeschle, P M, Feorino, G, McCord   +3 more
openaire   +3 more sources

The role of Coxsackievirus A16 in a case of sudden unexplained death in an infant – A SUDI case

Forensic Science International, 2016
The Coxsackievirus A16 (CV-A16) is one of the main pathogens causing hand-foot-and-mouth disease in young children. It is a low-virulence virus rarely involved in serious illness. It is seen sporadically or in outbreaks all over the world. We report a case of sudden unexplained death in infancy, SUDI, in a 3 and 1/2 months old infant, in which a ...
B.S. Astrup, I.B.G. Johnsen, A.L. Engsbro   +2 more
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Molecular Analysis of Coxsackievirus A16 Reveals a New Genetic Group of Enteroviruses

Virology, 1994
Coxsackievirus A16 (CAV16) a member of the Enterovirus genus of Picornaviridae, is associated with hand-foot-and-mouth disease, a febrile papulovesicular rash of childhood. We have determined the complete nucleotide sequence of the genome of the prototype strain of CAV16 which consists of 7413 nucleotides plus the poly(A) tail.
T, Pöyry, T, Hyypiä, C, Horsnell, L, Kinnunen, T, Hovi, G, Stanway   +5 more
openaire   +2 more sources

Characterization of cross-reactivity of coxsackievirus A2 VP1-specific polyclonal antibodies with enterovirus A71, coxsackievirus A16, and coxsackievirus A6

Virology
Coxsackievirus A2 (CVA2) is associated with multiple diseases in children. Currently, there is limited research on immunological detection methods for CVA2. Herein, the VP1 gene of CVA2 strain 201711, belonging to cluster 2 within genotype D, was analyzed.
Ling Tao, Yawen Yang, Hejun Liu, Liang Yi, Jingyi Cao, Pengwei Xu, Qian Zhao, Yinlan Xu, Fengquan Zhang, Dong Liu, Weidong Wu, Yuefei Jin   +11 more
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An adult gerbil model for evaluating potential coxsackievirus A16 vaccine candidates

Vaccine, 2019
A suitable animal model of CVA16 infection is crucial in order to understand its pathogenesis and to help develop antiviral vaccines or screen therapeutic drugs. The neonatal mouse model has a short sensitivity period to CA16 infection, which is a major limitation.
Ping-Ping, Yao, Zi-Ping, Miao, Fang, Xu, Hang-Jing, Lu, Yi-Sheng, Sun, Yong, Xia, Chen, Chen, Zhang-Nv, Yang, Shi-Chang, Xia, Jian-Min, Jiang, Chong-Gao, Hu, Zi-An, Mao, Meng, Gao, Zhi-Yao, Xu, Han-Ning, Ying, Chen-Hui, Yao, Zhi-Yong, Zhu, Han-Ping, Zhu, Hai-Qing, Xiang   +18 more
openaire   +2 more sources