Acute Fulminant Cerebral Edema Caused by Coxsackievirus A6 Infection: A Case Report [PDF]
Clinical Case ReportsIn recent years, Coxsackievirus A6 (CV‐A6) has gradually replaced Enterovirus 71 (EV‐71) and Coxsackievirus A16 (CV‐A16) as the main pathogen causing hand foot mouth disease (HFMD) in China.
Kang An, Juan Qian
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Epidemiological Characteristics of Coxsackievirus A6 in Baotou, Inner Mongolia, China, 2023–2024 [PDF]
VirusesThe re-emergence of Coxsackievirus A6 (CV-A6) as a predominant pathogen in hand, foot, and mouth disease (HFMD) underscores the need for ongoing molecular surveillance to clarify local evolutionary dynamics.
Chenxi Zhang +11 more
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A review of the recombination events, mechanisms and consequences of Coxsackievirus A6 [PDF]
Infectious MedicineHand, foot, and mouth disease (HFMD) is one of the most common class C infectious diseases, posing a serious threat to public health worldwide. Enterovirus A71 (EV-A71) and coxsackievirus A16 (CV-A16) have been regarded as the major pathogenic agents of ...
Zequn Wang, Hongling Wen
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Cryo-electron microscopy and image classification reveal the existence and structure of the coxsackievirus A6 virion [PDF]
Communications Biology, 2022 A cryo-EM structure for the three conformers of coxsackievirus A6 provides insight into the infection process of this enterovirus, which is responsible for numerous cases of hand, foot, and mouth disease.
Carina R. Büttner +3 more
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Clinical Features and Characteristics of Hand, Foot, and Mouth Disease Caused by Recent Coxsackievirus A6: Five Cases in Japan from 2019 to 2022 [PDF]
Infectious Disease ReportsHand, foot, and mouth disease (HFMD) is a common infectious disease caused by enteroviruses. Coxsackievirus A6 (CV-A6)-associated HFMD has recently emerged as a predominant disease worldwide.
Kyohei Naomiya +6 more
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Recent advances on coxsackievirus A6 vaccine research [PDF]
Frontiers in ImmunologyBackgroundHand, foot, and mouth disease (HFMD) is an acute infectious disease caused by human enteroviruses (EVs). EVs are most prevalent in children under five years of age and have the potential to result in herpangina, HFMD, and severe complications ...
Xianfeng Zhou +7 more
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Coxsackievirus A6 Infection Causes Neurogenic Pathogenesis in a Neonatal Murine Model [PDF]
Viruses, 2023 Coxsackievirus A6 (CVA6), a member of species A enterovirus, is associated with outbreaks of hand-foot-and-mouth disease and causes a large nationwide burden of disease. However, the molecular pathogenesis of CVA6 remains unclear.
Qiang Sun +9 more
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Evolutionary and Genetic Recombination Analyses of Coxsackievirus A6 Variants Associated with Hand, Foot, and Mouth Disease Outbreaks in Thailand between 2019 and 2022 [PDF]
Viruses, 2022 Coxsackievirus (CV)-A6 infections cause hand, foot, and mouth disease (HFMD) in children and adults. Despite the serious public health threat presented by CV-A6 infections, our understanding of the mechanisms by which new CV-A6 strains emerge remains ...
Jiratchaya Puenpa +7 more
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Efficacy of a coxsackievirus A6 vaccine candidate in an actively immunized mouse model [PDF]
Emerging Microbes and Infections, 2021 Coxsackievirus A6 (CV-A6) has been emerging as a major pathogen of hand, foot and mouth disease (HFMD). Study on the pathogenesis of CV-A6 infection and development of vaccines is hindered by a lack of appropriate animal models.
Sha-Sha Qian +8 more
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An Outbreak of Coxsackievirus A6 Infection in Adults of a Collective Unit, China, 2019 [PDF]
Canadian Journal of Infectious Diseases and Medical Microbiology, 2022 Outbreaks/epidemics caused by coxsackievirus A6 (CVA6) have been reported continuously since 2008. However, outbreaks of ocular conjunctival hemorrhage caused by CVA6 in adults in a collective unit have not been reported. Methods.
Yumeng Gao +8 more
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