Results 131 to 140 of about 148,572 (261)
Human SART3 has two RRM domains to engage with U6 snRNA for spliceosome recycling. This study reports solution structures of SART3 RRM domains and investigates the interaction between RRM and U6 snRNA. SART3 binds to the asymmetric bulge of U6 snRNA as a dimer via conserved positively charged surfaces.
Iktae Kim +8 more
wiley +1 more source
<i>Macaranga peltata</i> Alleviates Neuropsychiatric Disorders in Mouse Model and Computational Study. [PDF]
The methanol extract of Macaranga peltata leaves (MEMPL) exhibited notable neuropharmacological and analgesic properties in rodents. Phytochemical and GC–MS analyses confirmed diverse bioactive compounds. MEMPL (200–400 mg/kg) showed anxiolytic, antidepressant, CNS depressant, and antinociceptive effects, comparable to standard drugs.
Tanzil SM +11 more
europepmc +2 more sources
Partial mass degeneracy and spontaneous CP violation in the lepton sector [PDF]
T. Araki, H. Ishida
openalex +1 more source
ABSTRACT Introduction The expansion of haemophilia treatment to include non‐factor prophylaxis provides new options with various benefits, risks, administration modes, and device types, necessitating trade‐offs in decision‐making. Aim This study evaluated prophylactic treatment preferences of people with haemophilia and their caregivers, assessing ...
Hui Lu +12 more
wiley +1 more source
Lateral ventricular choroid plexus enlargement in patients with spontaneous intracranial hypotension
Abstract Objective This study aimed to evaluate the choroid plexus volume in patients with spontaneous intracranial hypotension (SIH), including the lateral, third, and fourth ventricles, and explore its potential relationship with clinical characteristics. Background SIH is caused by cerebrospinal fluid (CSF) leaks. The choroid plexus is predominantly
Sojung Yoon +6 more
wiley +1 more source
An Uncertainty Based Approach for Dealing With Selection Bias in Non‐Probability Samples
Summary The main issue with non‐probability samples is that the standard design‐based approach cannot be applied as the selection mechanism is unknown. In this paper, the concept of uncertainty on data generating model, resulting from the lack of knowledge of the sampling design acting in the non‐probability sample, is discussed.
Pier Luigi Conti, Daniela Marella
wiley +1 more source
Abstract This paper introduces a novel heuristic method, the smart selective navigator (SSN), for addressing arc routing problems (ARPs) with a focus on integrating hard turn restrictions in urban winter operations. Addressing a significant gap in existing ARP methodologies, SSN seamlessly incorporates common side constraints, such as vehicle ...
Farhad Baghyari, Jaho Seo
wiley +1 more source

