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Scandinavian Actuarial Journal, 1963
Abstract 1. In a s. or n.s. cPp (stationary or non-stationary compound Poisson process) the probability for occurrence of m events, while the parameter (one-or more-dimensional) passes from zero to τ 0 as measured on an absolute scale (the τ-scale), is defined as a mean of Poisson probabilities with intensities, which are distributed with distribution ...
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Abstract 1. In a s. or n.s. cPp (stationary or non-stationary compound Poisson process) the probability for occurrence of m events, while the parameter (one-or more-dimensional) passes from zero to τ 0 as measured on an absolute scale (the τ-scale), is defined as a mean of Poisson probabilities with intensities, which are distributed with distribution ...
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Comparison of CPP Uptake Methods
2010In the last 15 years, an ever expanding pool of cell-penetrating peptides (CPPs) has been discovered and recently focus has shifted towards improving already existing CPPs by different modifications. Since the number of published peptide sequences with cell-penetrating ability is now reaching several hundreds, the consensus methods to compare the ...
Tina, Holm +2 more
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Intracellular Delivery of Nanoparticles with CPPs
2010Cell-penetrating peptides (CPPs), in particular TATp, have been widely used for intracellular delivery of various cargoes, both in vitro and in vivo. Modifications of nanoparticles with CPPs require either covalent or noncovalent approach. Here we describe various methods to attach CPP, such as TATp to surface of nanocarriers (such as liposomes and ...
Rupa, Sawant, Vladimir, Torchilin
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Measurements of the Intracellular Stability of CPPs
2010Nowadays, the analysis of the uptake and intracellular distribution of cell-penetrating peptides mostly relies on fluorescence microscopy, using fluorescently labeled CPP analogs. However, fluorescence microscopy does not reveal to which degree fluorescence reflects the intact peptide or only breakdown products.
Ruttekolk, I.R.R. +3 more
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Application of CPPs for Brain Delivery
2015Cell-penetrating peptides provide a promising strategy for delivery of drugs across the blood-brain barrier. Here, we present an overview of CPP and peptide-mediated delivery to the central nervous system as well as a Transwell in vitro model to evaluate passage across an endothelial cell layer mimic of the blood-brain barrier.
Artita, Srimanee +2 more
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