Results 1 to 10 of about 5,199,365 (284)
Cell-Penetrating Peptides and Transportan [PDF]
Pharmaceutics, 2021 In the most recent 25–30 years, multiple novel mechanisms and applications of cell-penetrating peptides (CPP) have been demonstrated, leading to novel drug delivery systems.
Ülo Langel
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Cell Penetrating Peptides, Novel Vectors for Gene Therapy
Pharmaceutics, 2020 Cell penetrating peptides (CPPs), also known as protein transduction domains (PTDs), first identified ~25 years ago, are small, 6−30 amino acid long, synthetic, or naturally occurring peptides, able to carry variety of cargoes across the cellular ...
Rebecca E. Taylor, Maliha Zahid
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Internalization mechanisms of cell-penetrating peptides
Beilstein Journal of Nanotechnology, 2020 In today’s modern era of medicine, macromolecular compounds such as proteins, peptides and nucleic acids are dethroning small molecules as leading therapeutics. Given their immense potential, they are highly sought after.
Ivana Ruseska, Andreas Zimmer
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Prediction of cell penetrating peptides by support vector machines. [PDF]
PLoS Computational Biology, 2011 Cell penetrating peptides (CPPs) are those peptides that can transverse cell membranes to enter cells. Once inside the cell, different CPPs can localize to different cellular components and perform different roles.
William S Sanders +4 more
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Cell Penetrating Peptides in the Delivery of Biopharmaceuticals
Biomolecules, 2012 The cell membrane is a highly selective barrier. This limits the cellular uptake of molecules including DNA, oligonucleotides, peptides and proteins used as therapeutic agents. Different approaches have been employed to increase the membrane permeability
Jianping Zhou +4 more
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Cell-Penetrating Peptides—Mechanisms of Cellular Uptake and Generation of Delivery Systems
Pharmaceuticals, 2010 The successful clinical application of nucleic acid-based therapeutic strategies has been limited by the poor delivery efficiency achieved by existing vectors. The development of alternative delivery systems for improved biological activity is, therefore,
Sara Trabulo +3 more
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Cell-Penetrating Milk-Derived Peptides with a Non-Inflammatory Profile
Molecules, 2023 Milk-derived peptides are known to confer anti-inflammatory effects. We hypothesised that milk-derived cell-penetrating peptides might modulate inflammation in useful ways.
Clement Agoni +8 more
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Designed Multifunctional Peptides for Intracellular Targets
Antibiotics, 2022 Nature’s way for bioactive peptides is to provide them with several related functions and the ability to cooperate in performing their job. Natural cell-penetrating peptides (CPP), such as penetratins, inspired the design of multifunctional constructs ...
Davor Juretić
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Selective Moonlighting Cell-Penetrating Peptides
Pharmaceutics, 2021 Cell penetrating peptides (CPPs) are molecules capable of passing through biological membranes. This capacity has been used to deliver impermeable molecules into cells, such as drugs and DNA probes, among others.
Rafael Morán-Torres +5 more
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Chemical-functional diversity in cell-penetrating peptides. [PDF]
PLoS ONE, 2013 Cell-penetrating peptides (CPPs) are a promising tool to overcome cell membrane barriers. They have already been successfully applied as carriers for several problematic cargoes, like e.g.
Sofie Stalmans +7 more
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